Wearable Electrochemical Biosensors for Advanced Healthcare Monitoring
Abstract Recent advancements in wearable electrochemical biosensors have opened new avenues for on‐body and continuous detection of biomarkers, enabling personalized, real‐time, and preventive healthcare. While glucose monitoring has set a precedent for wearable biosensors, the field is rapidly expa...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Advanced Science |
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| Online Access: | https://doi.org/10.1002/advs.202411433 |
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| author | Haowei Duan Shuhua Peng Shuai He Shi‐Yang Tang Keisuke Goda Chun H. Wang Ming Li |
| author_facet | Haowei Duan Shuhua Peng Shuai He Shi‐Yang Tang Keisuke Goda Chun H. Wang Ming Li |
| author_sort | Haowei Duan |
| collection | DOAJ |
| description | Abstract Recent advancements in wearable electrochemical biosensors have opened new avenues for on‐body and continuous detection of biomarkers, enabling personalized, real‐time, and preventive healthcare. While glucose monitoring has set a precedent for wearable biosensors, the field is rapidly expanding to include a wider range of analytes crucial for disease diagnosis, treatment, and management. In this review, recent key innovations are examined in the design and manufacturing underpinning these biosensing platforms including biorecognition elements, signal transduction methods, electrode and substrate materials, and fabrication techniques. The applications of these biosensors are then highlighted in detecting a variety of biochemical markers, such as small molecules, hormones, drugs, and macromolecules, in biofluids including interstitial fluid, sweat, wound exudate, saliva, and tears. Additionally, the review also covers recent advances in wearable electrochemical biosensing platforms, such as multi‐sensory integration, closed‐loop control, and power supply. Furthermore, the challenges associated with critical issues are discussed, such as biocompatibility, biofouling, and sensor degradation, and the opportunities in materials science, nanotechnology, and artificial intelligence to overcome these limitations. |
| format | Article |
| id | doaj-art-908b4bf98c3d4a74882873132e55ecf8 |
| institution | Kabale University |
| issn | 2198-3844 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj-art-908b4bf98c3d4a74882873132e55ecf82025-01-13T15:29:43ZengWileyAdvanced Science2198-38442025-01-01122n/an/a10.1002/advs.202411433Wearable Electrochemical Biosensors for Advanced Healthcare MonitoringHaowei Duan0Shuhua Peng1Shuai He2Shi‐Yang Tang3Keisuke Goda4Chun H. Wang5Ming Li6School of Mechanical and Manufacturing Engineering The University of New South Wales Sydney NSW 2052 AustraliaSchool of Mechanical and Manufacturing Engineering The University of New South Wales Sydney NSW 2052 AustraliaSchool of Mechanical and Manufacturing Engineering The University of New South Wales Sydney NSW 2052 AustraliaSchool of Mechanical and Manufacturing Engineering The University of New South Wales Sydney NSW 2052 AustraliaDepartment of Chemistry The University of Tokyo Tokyo 113‐0033 JapanSchool of Mechanical and Manufacturing Engineering The University of New South Wales Sydney NSW 2052 AustraliaSchool of Mechanical and Manufacturing Engineering The University of New South Wales Sydney NSW 2052 AustraliaAbstract Recent advancements in wearable electrochemical biosensors have opened new avenues for on‐body and continuous detection of biomarkers, enabling personalized, real‐time, and preventive healthcare. While glucose monitoring has set a precedent for wearable biosensors, the field is rapidly expanding to include a wider range of analytes crucial for disease diagnosis, treatment, and management. In this review, recent key innovations are examined in the design and manufacturing underpinning these biosensing platforms including biorecognition elements, signal transduction methods, electrode and substrate materials, and fabrication techniques. The applications of these biosensors are then highlighted in detecting a variety of biochemical markers, such as small molecules, hormones, drugs, and macromolecules, in biofluids including interstitial fluid, sweat, wound exudate, saliva, and tears. Additionally, the review also covers recent advances in wearable electrochemical biosensing platforms, such as multi‐sensory integration, closed‐loop control, and power supply. Furthermore, the challenges associated with critical issues are discussed, such as biocompatibility, biofouling, and sensor degradation, and the opportunities in materials science, nanotechnology, and artificial intelligence to overcome these limitations.https://doi.org/10.1002/advs.202411433biomarkersbody fluidselectrochemical biosensorshealthcare monitoringwearable electronics |
| spellingShingle | Haowei Duan Shuhua Peng Shuai He Shi‐Yang Tang Keisuke Goda Chun H. Wang Ming Li Wearable Electrochemical Biosensors for Advanced Healthcare Monitoring Advanced Science biomarkers body fluids electrochemical biosensors healthcare monitoring wearable electronics |
| title | Wearable Electrochemical Biosensors for Advanced Healthcare Monitoring |
| title_full | Wearable Electrochemical Biosensors for Advanced Healthcare Monitoring |
| title_fullStr | Wearable Electrochemical Biosensors for Advanced Healthcare Monitoring |
| title_full_unstemmed | Wearable Electrochemical Biosensors for Advanced Healthcare Monitoring |
| title_short | Wearable Electrochemical Biosensors for Advanced Healthcare Monitoring |
| title_sort | wearable electrochemical biosensors for advanced healthcare monitoring |
| topic | biomarkers body fluids electrochemical biosensors healthcare monitoring wearable electronics |
| url | https://doi.org/10.1002/advs.202411433 |
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