Nanotechnology-Enhanced Orthopaedic Surgery

Nanomaterials hold significant promise for the future of orthopaedic implants due to their ability to mimic the nanoscale components of the bone, such as collagen fibrils and hydroxyapatite. Nanomaterials can regulate cell behaviour while offering mechanical strength and biocompatibility, making the...

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Main Authors: Alexander Shao-Rong Pang, Zi Qiang Glen Liau, Jacob Yoong-Leong Oh, Dinesh Kumar Srinivasan
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Journal of Nanotheranostics
Subjects:
Online Access:https://www.mdpi.com/2624-845X/5/4/11
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author Alexander Shao-Rong Pang
Zi Qiang Glen Liau
Jacob Yoong-Leong Oh
Dinesh Kumar Srinivasan
author_facet Alexander Shao-Rong Pang
Zi Qiang Glen Liau
Jacob Yoong-Leong Oh
Dinesh Kumar Srinivasan
author_sort Alexander Shao-Rong Pang
collection DOAJ
description Nanomaterials hold significant promise for the future of orthopaedic implants due to their ability to mimic the nanoscale components of the bone, such as collagen fibrils and hydroxyapatite. Nanomaterials can regulate cell behaviour while offering mechanical strength and biocompatibility, making them ideal for bone repair and tissue regeneration. This comprehensive review explores the key existing and potential applications of nanotechnology in orthopaedics, including bone tissue engineering, drug delivery systems, systems combatting implant-related infections, and the surface preparation of implants to enhance osseointegration. These innovations are poised to revolutionise orthopaedic care by improving implant durability, reducing infection risks, and promoting bone regeneration to deliver personalised treatment and create better patient outcomes.
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institution Kabale University
issn 2624-845X
language English
publishDate 2024-11-01
publisher MDPI AG
record_format Article
series Journal of Nanotheranostics
spelling doaj-art-907c3249ac7f421ba34a9b8b15e1de372024-12-27T14:33:47ZengMDPI AGJournal of Nanotheranostics2624-845X2024-11-015416718710.3390/jnt5040011Nanotechnology-Enhanced Orthopaedic SurgeryAlexander Shao-Rong Pang0Zi Qiang Glen Liau1Jacob Yoong-Leong Oh2Dinesh Kumar Srinivasan3Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, SingaporeDepartment of Orthopaedic Surgery, National University Hospital, Singapore 119074, SingaporeSpine Division, Department of Orthopaedic Surgery, Tan Tock Seng Hospital, Singapore 308433, SingaporeDepartment of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117594, SingaporeNanomaterials hold significant promise for the future of orthopaedic implants due to their ability to mimic the nanoscale components of the bone, such as collagen fibrils and hydroxyapatite. Nanomaterials can regulate cell behaviour while offering mechanical strength and biocompatibility, making them ideal for bone repair and tissue regeneration. This comprehensive review explores the key existing and potential applications of nanotechnology in orthopaedics, including bone tissue engineering, drug delivery systems, systems combatting implant-related infections, and the surface preparation of implants to enhance osseointegration. These innovations are poised to revolutionise orthopaedic care by improving implant durability, reducing infection risks, and promoting bone regeneration to deliver personalised treatment and create better patient outcomes.https://www.mdpi.com/2624-845X/5/4/11orthopaedic surgerynanoparticlesnanotechnologybone tissue engineeringarthroplasty
spellingShingle Alexander Shao-Rong Pang
Zi Qiang Glen Liau
Jacob Yoong-Leong Oh
Dinesh Kumar Srinivasan
Nanotechnology-Enhanced Orthopaedic Surgery
Journal of Nanotheranostics
orthopaedic surgery
nanoparticles
nanotechnology
bone tissue engineering
arthroplasty
title Nanotechnology-Enhanced Orthopaedic Surgery
title_full Nanotechnology-Enhanced Orthopaedic Surgery
title_fullStr Nanotechnology-Enhanced Orthopaedic Surgery
title_full_unstemmed Nanotechnology-Enhanced Orthopaedic Surgery
title_short Nanotechnology-Enhanced Orthopaedic Surgery
title_sort nanotechnology enhanced orthopaedic surgery
topic orthopaedic surgery
nanoparticles
nanotechnology
bone tissue engineering
arthroplasty
url https://www.mdpi.com/2624-845X/5/4/11
work_keys_str_mv AT alexandershaorongpang nanotechnologyenhancedorthopaedicsurgery
AT ziqiangglenliau nanotechnologyenhancedorthopaedicsurgery
AT jacobyoongleongoh nanotechnologyenhancedorthopaedicsurgery
AT dineshkumarsrinivasan nanotechnologyenhancedorthopaedicsurgery