Population pharmacokinetics of selexipag for dose selection and confirmation in pediatric patients with pulmonary arterial hypertension
Abstract Selexipag is an oral selective prostacyclin receptor agonist approved for the treatment of pulmonary arterial hypertension (PAH) in adults. To date, no treatment targeting the prostacyclin pathway is approved for pediatric patients. Our goal is to identify a pediatric dose regimen that resu...
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| Main Authors: | Lene Nygaard Axelsen, Anne Kümmel, Juan Jose Perez Ruixo, Alberto Russu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-12-01
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| Series: | CPT: Pharmacometrics & Systems Pharmacology |
| Online Access: | https://doi.org/10.1002/psp4.13231 |
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