Eupalinolide B inhibits periodontitis development by targeting ubiquitin conjugating enzyme UBE2D3

Eupalinolide B inhibits periodontitis development by targeting ubiquitin conjugating enzyme UBE2D3

Abstract Periodontitis is a chronic periodontal inflammatory disease caused by periodontal pathogens commonly seen in adults. Eupalinolide B (EB) is a sesquiterpenoid natural product extracted from Eupatorium lindleyanum and has been reported as a potential drug for cancers and immune disorders. Her...

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Main Authors: Wenhua Kuang, Ruishen Zhuge, Ping Song, Letai Yi, Shujie Zhang, Ying Zhang, Yin Kwan Wong, Ruixing Chen, Junzhe Zhang, Yuanbo Wang, Dandan Liu, Zipeng Gong, Peili Wang, Xiangying Ouyang, Jigang Wang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:MedComm
Subjects:
chemical biology
drug targets
natural product
proteomics
target identification
Online Access:https://doi.org/10.1002/mco2.70034
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