A CRISPR-Cas9 system protecting E. coli against acquisition of antibiotic resistance genes

A CRISPR-Cas9 system protecting E. coli against acquisition of antibiotic resistance genes

Abstract Antimicrobial resistance (AMR) is an increasing problem worldwide, and new treatment options for bacterial infections are direly needed. Engineered probiotics show strong potential in treating or preventing bacterial infections. However, one concern with the use of live bacteria is the risk...

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Bibliographic Details
Main Authors: Danna Lee, Petra Muir, Sara Lundberg, August Lundholm, Linus Sandegren, Sanna Koskiniemi
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-85334-2
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