Human genetic variation determines 24-hour rhythmic gene expression and disease risk
Abstract 24-hour biological rhythms are essential to maintain physiological homeostasis. Disruption of these rhythms increases the risks of multiple diseases. Biological rhythms are known to have a genetic basis formed by core clock genes, but how individual genetic variation shapes the oscillating...
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| Main Authors: | Ying Chen, Panpan Liu, Aniko Sabo, Dongyin Guan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-59524-5 |
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