Total glucosides of Picrorhizae Rhizome alleviate non-alcoholic steatohepatitis (NASH) by specifically targeting acyl-CoA oxidase 1

Total glucosides of Picrorhizae Rhizome alleviate non-alcoholic steatohepatitis (NASH) by specifically targeting acyl-CoA oxidase 1

Nonalcoholic steatohepatitis (NASH), a chronic liver disease characterized by the accumulation of fat in the liver, is highly prevalent on a global scale. In this study, we investigated the effects of total glucosides of Picrorhizae Rhizome (TGPR), the primary active ingredients in traditional Chine...

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Bibliographic Details
Main Authors:	Fang-Fang Zhuo, Xiao-Qing Li, Jun Zhang, Fu-Ming Zhang, Zhao-Hui Song, Yi He, Li Ding, Dan Liu, Peng-Fei Tu, Xiao-Hui Ma, Ke-Wu Zeng
Format:	Article
Language:	English
Published:	Elsevier 2024-11-01
Series:	Heliyon
Subjects:	Nonalcoholic steatohepatitis (NASH) Total glucosides of Picrorhizae Rhizome Target identification Acyl-CoA oxidase 1 (Acox1) Fatty acids
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024159051
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