Virtual screening and lead optimization of Desmostachya bipinnata-derived FGFR inhibitors for oral squamous cell carcinoma management

Virtual screening and lead optimization of Desmostachya bipinnata-derived FGFR inhibitors for oral squamous cell carcinoma management

Background: Oral cancer remains a major global health challenge with limited therapeutic options, highlighting the need for novel treatments. Phytochemicals derived from Desmostachya bipinnata (Db), a plant used in traditional Chinese medicine for its anti-inflammatory and analgesic properties, have...

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Bibliographic Details
Main Authors: Nitya Krishnasamy, Ramya Ramadoss, Swarnalakshmi Raman
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Pharmacological Research - Modern Chinese Medicine
Subjects:
Oral cancer
OSCC
Fibroblast growth factor
Docking
Anti-cancer
Desmostachya bipinnata
Online Access:http://www.sciencedirect.com/science/article/pii/S2667142524001763
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