Patterns of substance use and associations with mental health and interpersonal violence among adolescents

Objective: To identify patterns of adolescent substance use and associated behavioral health characteristics among adolescents. Methods: We conducted a cross-sectional study of 167,504 adolescents aged 13–17 who were screened for substance use, mental health symptoms, and interpersonal violence duri...

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Main Authors: Shannon N. Ogden, Catherine Cortez, Stacy A. Sterling, Stacey E. Alexeeff, Natalie E. Slama, Cynthia I. Campbell, Derek D. Satre, Asma H. Asyyed, Monique B. Does, Andrea Altschuler, Yun Lu, Kelly C. Young-Wolff
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Addictive Behaviors Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S235285322500015X
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author Shannon N. Ogden
Catherine Cortez
Stacy A. Sterling
Stacey E. Alexeeff
Natalie E. Slama
Cynthia I. Campbell
Derek D. Satre
Asma H. Asyyed
Monique B. Does
Andrea Altschuler
Yun Lu
Kelly C. Young-Wolff
author_facet Shannon N. Ogden
Catherine Cortez
Stacy A. Sterling
Stacey E. Alexeeff
Natalie E. Slama
Cynthia I. Campbell
Derek D. Satre
Asma H. Asyyed
Monique B. Does
Andrea Altschuler
Yun Lu
Kelly C. Young-Wolff
author_sort Shannon N. Ogden
collection DOAJ
description Objective: To identify patterns of adolescent substance use and associated behavioral health characteristics among adolescents. Methods: We conducted a cross-sectional study of 167,504 adolescents aged 13–17 who were screened for substance use, mental health symptoms, and interpersonal violence during well-check visits in a large healthcare system in California from 2021 to 2022. We conducted latent class analysis to identify patterns of substance use from four substance use behaviors (past-year alcohol, cannabis, other substance, and close friends’ use). We calculated the prevalence of depressive symptoms, suicidal ideation, bullying, physical abuse by an adult, sexual violence, and intimate partner violence for each substance use class compared to those with no reported substance use behaviors and estimated adjusted prevalence ratios using modified Poisson regression. Results: In total, 29,288 (17 %) adolescents reported ≥ 1 substance use characteristic. From those, we identified five latent classes with different patterns of substance use: substance use among close friends (37 %), alcohol use (21 %), polysubstance use (20 %), cannabis use and some polysubstance use (18 %), and other substance use (5 %). All classes had higher adjusted prevalence of mental health and interpersonal violence outcomes compared to those with no substance use characteristics, with the greatest differences being among the polysubstance use class. Conclusions: The high prevalence of mental health and interpersonal violence outcomes among adolescents with substance use, even among those who only report close friends’ substance use, highlights the need for routine screening during well-check visits. Comprehensive routine social and behavioral health screening among adolescents is vital for early identification and intervention.
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spelling doaj-art-8fa63fa4b2ac4ab8a57ac4e8a28b45b82025-08-20T03:19:56ZengElsevierAddictive Behaviors Reports2352-85322025-06-012110059710.1016/j.abrep.2025.100597Patterns of substance use and associations with mental health and interpersonal violence among adolescentsShannon N. Ogden0Catherine Cortez1Stacy A. Sterling2Stacey E. Alexeeff3Natalie E. Slama4Cynthia I. Campbell5Derek D. Satre6Asma H. Asyyed7Monique B. Does8Andrea Altschuler9Yun Lu10Kelly C. Young-Wolff11Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, USA; Corresponding author at: Division of Research, Kaiser Permanente Northern California, 4480 Hacienda Dr, Bldg B, Pleasanton, CA 94588, USA.Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, USADivision of Research, Kaiser Permanente Northern California, Pleasanton, CA, USA; Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, CA, USADivision of Research, Kaiser Permanente Northern California, Pleasanton, CA, USADivision of Research, Kaiser Permanente Northern California, Pleasanton, CA, USADivision of Research, Kaiser Permanente Northern California, Pleasanton, CA, USA; Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, CA, USADivision of Research, Kaiser Permanente Northern California, Pleasanton, CA, USA; Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, CA, USARegional Offices, Kaiser Permanente Northern California, Pleasanton, CA, USADivision of Research, Kaiser Permanente Northern California, Pleasanton, CA, USADivision of Research, Kaiser Permanente Northern California, Pleasanton, CA, USADivision of Research, Kaiser Permanente Northern California, Pleasanton, CA, USADivision of Research, Kaiser Permanente Northern California, Pleasanton, CA, USA; Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, CA, USAObjective: To identify patterns of adolescent substance use and associated behavioral health characteristics among adolescents. Methods: We conducted a cross-sectional study of 167,504 adolescents aged 13–17 who were screened for substance use, mental health symptoms, and interpersonal violence during well-check visits in a large healthcare system in California from 2021 to 2022. We conducted latent class analysis to identify patterns of substance use from four substance use behaviors (past-year alcohol, cannabis, other substance, and close friends’ use). We calculated the prevalence of depressive symptoms, suicidal ideation, bullying, physical abuse by an adult, sexual violence, and intimate partner violence for each substance use class compared to those with no reported substance use behaviors and estimated adjusted prevalence ratios using modified Poisson regression. Results: In total, 29,288 (17 %) adolescents reported ≥ 1 substance use characteristic. From those, we identified five latent classes with different patterns of substance use: substance use among close friends (37 %), alcohol use (21 %), polysubstance use (20 %), cannabis use and some polysubstance use (18 %), and other substance use (5 %). All classes had higher adjusted prevalence of mental health and interpersonal violence outcomes compared to those with no substance use characteristics, with the greatest differences being among the polysubstance use class. Conclusions: The high prevalence of mental health and interpersonal violence outcomes among adolescents with substance use, even among those who only report close friends’ substance use, highlights the need for routine screening during well-check visits. Comprehensive routine social and behavioral health screening among adolescents is vital for early identification and intervention.http://www.sciencedirect.com/science/article/pii/S235285322500015XAdolescent healthInterpersonal violenceMental healthSubstance use
spellingShingle Shannon N. Ogden
Catherine Cortez
Stacy A. Sterling
Stacey E. Alexeeff
Natalie E. Slama
Cynthia I. Campbell
Derek D. Satre
Asma H. Asyyed
Monique B. Does
Andrea Altschuler
Yun Lu
Kelly C. Young-Wolff
Patterns of substance use and associations with mental health and interpersonal violence among adolescents
Addictive Behaviors Reports
Adolescent health
Interpersonal violence
Mental health
Substance use
title Patterns of substance use and associations with mental health and interpersonal violence among adolescents
title_full Patterns of substance use and associations with mental health and interpersonal violence among adolescents
title_fullStr Patterns of substance use and associations with mental health and interpersonal violence among adolescents
title_full_unstemmed Patterns of substance use and associations with mental health and interpersonal violence among adolescents
title_short Patterns of substance use and associations with mental health and interpersonal violence among adolescents
title_sort patterns of substance use and associations with mental health and interpersonal violence among adolescents
topic Adolescent health
Interpersonal violence
Mental health
Substance use
url http://www.sciencedirect.com/science/article/pii/S235285322500015X
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