NVP-2, in combination with Orlistat, represents a promising therapeutic strategy for acute myeloid leukemia

NVP-2, in combination with Orlistat, represents a promising therapeutic strategy for acute myeloid leukemia

Cell cycle dysregulation and the corresponding metabolic reprogramming play significant roles in tumor development and progression. CDK9, a kinase that regulates gene transcription and cell cycle, also induces oncogene transcription and abnormal cell cycle in AML cells. The function of CDK9 for gene...

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Bibliographic Details
Main Authors: Qing Zhu, Jia Cheng, Yuqing Gao, Zimu Zhang, Jian Pan, Xin Su, Danhong Fei, Linbo Cai, Juanjuan Yu, Yanling Chen, Wanyan Jiao, Di Wu, Xiaolu Li, Peifang Xiao
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Cancer Biology & Therapy
Subjects:
Acute myeloid leukemia
apoptosis
CDK9
cell proliferation
c-Myc
FASN
Online Access:https://www.tandfonline.com/doi/10.1080/15384047.2025.2450859
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