Tracheobronchial amyloidosis following COVID‐19 infection

Abstract Deposition of amyloid proteins in extracellular space can occur due to uncontrolled inflammatory processes. Tracheobronchial amyloidosis (TBA) is a rare form of such disease. A 68‐year‐old woman was evaluated for chronic cough following a COVID‐19 infection. Although post‐viral sequelae wer...

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Main Authors: Chathurangi Angammana, Sameera Gamlath, Ravini Karunathilake, Shehan Silva
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Respirology Case Reports
Subjects:
Online Access:https://doi.org/10.1002/rcr2.70073
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author Chathurangi Angammana
Sameera Gamlath
Ravini Karunathilake
Shehan Silva
author_facet Chathurangi Angammana
Sameera Gamlath
Ravini Karunathilake
Shehan Silva
author_sort Chathurangi Angammana
collection DOAJ
description Abstract Deposition of amyloid proteins in extracellular space can occur due to uncontrolled inflammatory processes. Tracheobronchial amyloidosis (TBA) is a rare form of such disease. A 68‐year‐old woman was evaluated for chronic cough following a COVID‐19 infection. Although post‐viral sequelae were suspected, further investigation revealed TBA. This condition involves amyloid deposits within the airways. The temporal association with COVID‐19 raises a potential etiological link, suggesting viral‐induced inflammatory or immune‐mediated processes may play a role. This case underlines the need to consider rare etiologies like TBA in patients with unresolved respiratory symptoms post‐COVID‐19.
format Article
id doaj-art-8f8769a6c7ff46edb4be2f11fe88d6ef
institution Kabale University
issn 2051-3380
language English
publishDate 2024-12-01
publisher Wiley
record_format Article
series Respirology Case Reports
spelling doaj-art-8f8769a6c7ff46edb4be2f11fe88d6ef2024-12-24T14:22:32ZengWileyRespirology Case Reports2051-33802024-12-011212n/an/a10.1002/rcr2.70073Tracheobronchial amyloidosis following COVID‐19 infectionChathurangi Angammana0Sameera Gamlath1Ravini Karunathilake2Shehan Silva3University Medical Unit Colombo South Teaching Hospital Dehiwala‐Mount Lavinia Sri LankaRespiratory Unit National Hospital of Sri Lanka Colombo Sri LankaRespiratory Unit National Hospital of Sri Lanka Colombo Sri LankaUniversity Medical Unit Colombo South Teaching Hospital Dehiwala‐Mount Lavinia Sri LankaAbstract Deposition of amyloid proteins in extracellular space can occur due to uncontrolled inflammatory processes. Tracheobronchial amyloidosis (TBA) is a rare form of such disease. A 68‐year‐old woman was evaluated for chronic cough following a COVID‐19 infection. Although post‐viral sequelae were suspected, further investigation revealed TBA. This condition involves amyloid deposits within the airways. The temporal association with COVID‐19 raises a potential etiological link, suggesting viral‐induced inflammatory or immune‐mediated processes may play a role. This case underlines the need to consider rare etiologies like TBA in patients with unresolved respiratory symptoms post‐COVID‐19.https://doi.org/10.1002/rcr2.70073COVID‐19serum amyloid Atracheobronchial amyloidosis
spellingShingle Chathurangi Angammana
Sameera Gamlath
Ravini Karunathilake
Shehan Silva
Tracheobronchial amyloidosis following COVID‐19 infection
Respirology Case Reports
COVID‐19
serum amyloid A
tracheobronchial amyloidosis
title Tracheobronchial amyloidosis following COVID‐19 infection
title_full Tracheobronchial amyloidosis following COVID‐19 infection
title_fullStr Tracheobronchial amyloidosis following COVID‐19 infection
title_full_unstemmed Tracheobronchial amyloidosis following COVID‐19 infection
title_short Tracheobronchial amyloidosis following COVID‐19 infection
title_sort tracheobronchial amyloidosis following covid 19 infection
topic COVID‐19
serum amyloid A
tracheobronchial amyloidosis
url https://doi.org/10.1002/rcr2.70073
work_keys_str_mv AT chathurangiangammana tracheobronchialamyloidosisfollowingcovid19infection
AT sameeragamlath tracheobronchialamyloidosisfollowingcovid19infection
AT ravinikarunathilake tracheobronchialamyloidosisfollowingcovid19infection
AT shehansilva tracheobronchialamyloidosisfollowingcovid19infection