Gastrointestinal jumbo phages possess independent synthesis and utilization systems of NAD+

Gastrointestinal jumbo phages possess independent synthesis and utilization systems of NAD+

Abstract Background Jumbo phages, phages with genomes > 200 kbp, contain some unique genes for successful reproduction in their bacterial hosts. Due to complex and massive genomes analogous to those of small-celled bacteria, how jumbo phages complete their life cycle remains largely undefined. Re...

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Bibliographic Details
Main Authors: Cunyuan Li, Kaiping Liu, Chengxiang Gu, Ming Li, Ping Zhou, Linxing Chen, Shize Sun, Xiaoyue Li, Limin Wang, Wei Ni, Meng Li, Shengwei Hu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Microbiome
Subjects:
Bacteriophage
Animal gut
Metagenome
NAD+
Jumbo phage
Online Access:https://doi.org/10.1186/s40168-024-01984-w
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