A transcription network underlies the dual genomic coordination of mitochondrial biogenesis

A transcription network underlies the dual genomic coordination of mitochondrial biogenesis

Mitochondrial biogenesis requires the expression of genes encoded by both the nuclear and mitochondrial genomes. However, aside from a handful transcription factors regulating specific subsets of mitochondrial genes, the overall architecture of the transcriptional control of mitochondrial biogenesis...

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Bibliographic Details
Main Authors: Fan Zhang, Annie Lee, Anna V Freitas, Jake T Herb, Zong-Heng Wang, Snigdha Gupta, Zhe Chen, Hong Xu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
mitochondrial biogenesis
transcription factors
TFAM
SDHA
ChIP-seq
RNA-seq
Online Access:https://elifesciences.org/articles/96536
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