Demultiplexing and barcode-specific adaptive sampling for nanopore direct RNA sequencing

Abstract Nanopore direct RNA sequencing (dRNA-seq) enables unique insights into RNA biology. However, applications are currently limited by the lack of accurate and cost-effective sample multiplexing. Here we introduce WarpDemuX, an ultra-fast and highly accurate adapter-barcoding and demultiplexing...

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Bibliographic Details
Main Authors: Wiep van der Toorn, Patrick Bohn, Wang Liu-Wei, Marco Olguin-Nava, Anne-Sophie Gribling-Burrer, Redmond P. Smyth, Max von Kleist
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59102-9
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