Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study
Abstract Background Depressive symptom is the most common type of psychiatric co-morbidity among persons with epilepsy. Epilepsy patients are identified as at higher risk of suffering depressive symptom explicitly in low- and middle-income countries due to poor mental health care systems and financi...
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2025-01-01
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| Online Access: | https://doi.org/10.1186/s13104-025-07080-y |
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| author | Sintayehu Simie Tsega Yilkal Abebaw Wassie Alebachew Ferede Zegeye Mekdes Kiflu Sisay Maru Wubante Kennean Mekonnen Birhaneslasie Gebeyehu Yazew Birye Dessalegn Mekonnen Yeshambel Andargie Tarekegn |
| author_facet | Sintayehu Simie Tsega Yilkal Abebaw Wassie Alebachew Ferede Zegeye Mekdes Kiflu Sisay Maru Wubante Kennean Mekonnen Birhaneslasie Gebeyehu Yazew Birye Dessalegn Mekonnen Yeshambel Andargie Tarekegn |
| author_sort | Sintayehu Simie Tsega |
| collection | DOAJ |
| description | Abstract Background Depressive symptom is the most common type of psychiatric co-morbidity among persons with epilepsy. Epilepsy patients are identified as at higher risk of suffering depressive symptom explicitly in low- and middle-income countries due to poor mental health care systems and financial burdens. The co-occurrence of depressive symptom among epilepsy patients deteriorates the prognosis of the disease and diminishes the quality of life of both the patients and their families. However, there is limited evidence on the prevalence of depressive symptom and associated factors in Ethiopia. Therefore, this study is intended to assess the prevalence of depressive symptom and associated factors among epilepsy patients attending in Amhara region, Ethiopia. Method A multi-center institution-based cross-sectional study was done among epilepsy patients attending at Amhara region, Ethiopia. The Hospital Anxiety Depression tool was used to assess depressive symptom. To determine the factors associated with depressive symptom, a binary logistic regression model was used. Adjusted Odds Ratio (AOR) with the 95% Confidence Interval (CI) was reported in the multivariable binary logistic regression analysis. Results About 406 participants were registered in the study with a response rate of 97.6%. The prevalence of depressive symptom among epilepsy patients was 53.9% [95%CI: 49.1%, 58.8%]. In the multivariable binary logistic regression analysis, taking polytherapy treatment [AOR = 1.87, 95% CI: 1.04, 3.36], perceived stigma [AOR = 5.73, 95%CI: 3.11, 10.55], poor antiepileptic medication adherence [AOR = 3.33, 95%CI: 1.30, 8.54] and having poor [AOR = 5.83, 95%CI: 2.44, 13.90] and moderate social support [AOR = 3.08, 95%CI: 1.34, 7.09] were significantly associated with depressive symptom. Conclusions This study revealed that the magnitude of depressive symptom among epilepsy patients in Ethiopia was relatively high and multiple factors determined the likelihood of depressive symptom. Thus, healthcare providers and concerned stakeholders should strengthen comprehensive health education to reduce the magnitude and consequences of depressive symptom among this segment of the population. Moreover, strong social support with special attention should be given to epilepsy patients. |
| format | Article |
| id | doaj-art-8f49a7b6567347fa88c4a1d8c6e03ae7 |
| institution | Kabale University |
| issn | 1756-0500 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
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| spelling | doaj-art-8f49a7b6567347fa88c4a1d8c6e03ae72025-01-12T12:06:48ZengBMCBMC Research Notes1756-05002025-01-0118111010.1186/s13104-025-07080-yPrevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional studySintayehu Simie Tsega0Yilkal Abebaw Wassie1Alebachew Ferede Zegeye2Mekdes Kiflu3Sisay Maru Wubante4Kennean Mekonnen5Birhaneslasie Gebeyehu Yazew6Birye Dessalegn Mekonnen7Yeshambel Andargie Tarekegn8Department of Medical Nursing, School of Nursing, College of Medicine and Health Science, University of GondarDepartment of Medical Nursing, School of Nursing, College of Medicine and Health Science, University of GondarDepartment of Medical Nursing, School of Nursing, College of Medicine and Health Science, University of GondarDepartment of Pharmacy, College of Health Sciences, Debre Markos UniversityDepartment of Health Informatics, Institute of Public Health, College of Medicine and Health Science, University of GondarDepartment of Emergency and critical care, School of nursing, College of Medicine and Health Science, University of GondarDepartment of Nursing, College of Medicine and Health Sciences, Injibara UniversityAmhara Public Health InstituteDepartment of Otorhinolaryngology (ENT), School of Medicine, College of Medicine and Health Science, University of GondarAbstract Background Depressive symptom is the most common type of psychiatric co-morbidity among persons with epilepsy. Epilepsy patients are identified as at higher risk of suffering depressive symptom explicitly in low- and middle-income countries due to poor mental health care systems and financial burdens. The co-occurrence of depressive symptom among epilepsy patients deteriorates the prognosis of the disease and diminishes the quality of life of both the patients and their families. However, there is limited evidence on the prevalence of depressive symptom and associated factors in Ethiopia. Therefore, this study is intended to assess the prevalence of depressive symptom and associated factors among epilepsy patients attending in Amhara region, Ethiopia. Method A multi-center institution-based cross-sectional study was done among epilepsy patients attending at Amhara region, Ethiopia. The Hospital Anxiety Depression tool was used to assess depressive symptom. To determine the factors associated with depressive symptom, a binary logistic regression model was used. Adjusted Odds Ratio (AOR) with the 95% Confidence Interval (CI) was reported in the multivariable binary logistic regression analysis. Results About 406 participants were registered in the study with a response rate of 97.6%. The prevalence of depressive symptom among epilepsy patients was 53.9% [95%CI: 49.1%, 58.8%]. In the multivariable binary logistic regression analysis, taking polytherapy treatment [AOR = 1.87, 95% CI: 1.04, 3.36], perceived stigma [AOR = 5.73, 95%CI: 3.11, 10.55], poor antiepileptic medication adherence [AOR = 3.33, 95%CI: 1.30, 8.54] and having poor [AOR = 5.83, 95%CI: 2.44, 13.90] and moderate social support [AOR = 3.08, 95%CI: 1.34, 7.09] were significantly associated with depressive symptom. Conclusions This study revealed that the magnitude of depressive symptom among epilepsy patients in Ethiopia was relatively high and multiple factors determined the likelihood of depressive symptom. Thus, healthcare providers and concerned stakeholders should strengthen comprehensive health education to reduce the magnitude and consequences of depressive symptom among this segment of the population. Moreover, strong social support with special attention should be given to epilepsy patients.https://doi.org/10.1186/s13104-025-07080-yAmhara regionAssociated factorsDepressive symptomEpilepsy |
| spellingShingle | Sintayehu Simie Tsega Yilkal Abebaw Wassie Alebachew Ferede Zegeye Mekdes Kiflu Sisay Maru Wubante Kennean Mekonnen Birhaneslasie Gebeyehu Yazew Birye Dessalegn Mekonnen Yeshambel Andargie Tarekegn Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study BMC Research Notes Amhara region Associated factors Depressive symptom Epilepsy |
| title | Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study |
| title_full | Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study |
| title_fullStr | Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study |
| title_full_unstemmed | Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study |
| title_short | Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study |
| title_sort | prevalence of depressive symptom and its associated factors among epilepsy patients in amhara region ethiopia cross sectional study |
| topic | Amhara region Associated factors Depressive symptom Epilepsy |
| url | https://doi.org/10.1186/s13104-025-07080-y |
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