Cuproptosis and its potential role in musculoskeletal disease

Cuproptosis, a recently identified form of copper-dependent cell death, arises from intracellular copper dyshomeostasis. As an essential trace element, copper plays a critical role in bioenergetic metabolism, redox regulation, and synaptic transmission. However, excessive copper exerts cytotoxic eff...

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Bibliographic Details
Main Authors: Ziyang Xiang, Huiling Mei, Honglin Wang, Xiaoyue Yao, Ji Rao, Wentao Zhang, Aoshuang Xu, Lin Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1570131/full
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