Effect of zinc supplementation on growth of preterm infants
Background and objectives: Nutritional deficits are almost universal in low-birthweight babies. This study aimed to show the effect of zinc supplementation on growth and certain hematological parameters in preterm infants. Methods: The current case-control study was carried out on 80 healthy prete...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Kurdistan Higher Council Of Medical Specialties
2022-06-01
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| Series: | Advanced Medical Journal |
| Subjects: | |
| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/11 |
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| Summary: | Background and objectives: Nutritional deficits are almost universal in low-birthweight
babies. This study aimed to show the effect of zinc supplementation on growth and certain
hematological parameters in preterm infants.
Methods: The current case-control study was carried out on 80 healthy preterm infants below 37 weeks of age divided into two groups. The first group was a zinc-supplemented group fed with breast milk exclusively and supplemented with zinc (2 mg/kg/day) since the first day of life. The second group was a non-zinc-supplemented group fed with breast milk exclusively (without zinc supplementation). Both groups were followed up at the age of 4 months for monitoring growth and determining serum zinc and hemoglobin levels.
Results: At the beginning of the study; there was no significant statistical difference between
the zinc supplemented & non zinc supplemented groups in weight (2.4±0.2 kg vs 2.5±0.4kg),
length (45.0±1.6 cm vs 45.2±1.5 cm) and occipitofrontal circumference (31.5±1.2 cm vs
31.5±1.1cm) respectively, but there was a statistically significant difference at 4 months follow up with regard to weight (6.2±0.3 kg vs 6.0±0.2 kg) and length (63.2±2.1 cm vs 61.1±2.0 cm). Also,there was a highly significant increase in serum hemoglobin levels (11.7±1.6 gm/dl vs 10.6±1.5gm/dl) and serum zinc level (101.2±8.1 µg/dl vs 84.1±7.0 µg/dl) in the zinc-supplemented group compared to the non-zinc-supplemented group at 4 months follow up.
Conclusion: Zinc supplementation was found to be effective to enhance the growth as well as
increasing serum zinc and hemoglobin levels in the early months of life of preterm infants.
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| ISSN: | 2958-8979 2957-3580 |