Topical application of heparin for the correction of ocular surface lesions

<br> Yartsev V.D.<br> <br> Scientific Research Institute of Eye Diseases, Moscow<br> <br> The article considers historical aspects of topical application of heparin in ophthalmology, it provides the description of anti-inflammatory action mechanism of heparin. The...

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Main Author: V.D. Yartsev
Format: Article
Language:Russian
Published: Prime-Media 2018-07-01
Series:РМЖ "Клиническая офтальмология"
Online Access:http://clinopht.com/upload/iblock/738/738db6bee97dcbf57b73098640df8c12.pdf
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author V.D. Yartsev
author_facet V.D. Yartsev
author_sort V.D. Yartsev
collection DOAJ
description <br> Yartsev V.D.<br> <br> Scientific Research Institute of Eye Diseases, Moscow<br> <br> The article considers historical aspects of topical application of heparin in ophthalmology, it provides the description of anti-inflammatory action mechanism of heparin. The study describes in detail the indications for application of heparin ointment or heparin eye-drops in mono- or complex-therapy of dry eye syndrome, traumatic and burn keratitis, in some types of keratopathy. The experience of Russian and foreign researchers is analyzed (51 source in total). The author comes to the conclusion that topical use of heparin is pathogenically justified in the treatment of different inflammatory, dystrophic and degenerative conditions of ocular surface. Special attention is given to the treatment of patients with corneal burn. Disinfectant properties of heparin were found to be useful for etiotropic treatment of the patients with conjunctivitis or keratitis in mono- or combined therapy. The new drug forms of heparin, such as ocular ointment and eye drops, enable to choose the dose of the drug individually and accurately for the patients with different pathology of ocular surface, thus personifying the treatment.<br> <br> <b>Key words:</b> heparin, artificial tear, ocular surface, dry eye syndrome, keratopathy, corneal burn, PARIN-POS<sup>®</sup>, HYLOPARIN-COMOD<sup>®</sup>.<br> <b>For citation:</b> Yartsev V.D. Topical application of heparin for the correction of ocular surface lesions. RMJ “Clinical&nbsp;ophthalmology”. 2018;2:97–101.<br>
format Article
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institution Kabale University
issn 2311-7729
2619-1571
language Russian
publishDate 2018-07-01
publisher Prime-Media
record_format Article
series РМЖ "Клиническая офтальмология"
spelling doaj-art-8f31cb1cfce949988722af8acaef70f02025-01-16T09:39:39ZrusPrime-MediaРМЖ "Клиническая офтальмология"2311-77292619-15712018-07-0118210112Topical application of heparin for the correction of ocular surface lesionsV.D. Yartsev0Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399<br> Yartsev V.D.<br> <br> Scientific Research Institute of Eye Diseases, Moscow<br> <br> The article considers historical aspects of topical application of heparin in ophthalmology, it provides the description of anti-inflammatory action mechanism of heparin. The study describes in detail the indications for application of heparin ointment or heparin eye-drops in mono- or complex-therapy of dry eye syndrome, traumatic and burn keratitis, in some types of keratopathy. The experience of Russian and foreign researchers is analyzed (51 source in total). The author comes to the conclusion that topical use of heparin is pathogenically justified in the treatment of different inflammatory, dystrophic and degenerative conditions of ocular surface. Special attention is given to the treatment of patients with corneal burn. Disinfectant properties of heparin were found to be useful for etiotropic treatment of the patients with conjunctivitis or keratitis in mono- or combined therapy. The new drug forms of heparin, such as ocular ointment and eye drops, enable to choose the dose of the drug individually and accurately for the patients with different pathology of ocular surface, thus personifying the treatment.<br> <br> <b>Key words:</b> heparin, artificial tear, ocular surface, dry eye syndrome, keratopathy, corneal burn, PARIN-POS<sup>®</sup>, HYLOPARIN-COMOD<sup>®</sup>.<br> <b>For citation:</b> Yartsev V.D. Topical application of heparin for the correction of ocular surface lesions. RMJ “Clinical&nbsp;ophthalmology”. 2018;2:97–101.<br>http://clinopht.com/upload/iblock/738/738db6bee97dcbf57b73098640df8c12.pdf
spellingShingle V.D. Yartsev
Topical application of heparin for the correction of ocular surface lesions
РМЖ "Клиническая офтальмология"
title Topical application of heparin for the correction of ocular surface lesions
title_full Topical application of heparin for the correction of ocular surface lesions
title_fullStr Topical application of heparin for the correction of ocular surface lesions
title_full_unstemmed Topical application of heparin for the correction of ocular surface lesions
title_short Topical application of heparin for the correction of ocular surface lesions
title_sort topical application of heparin for the correction of ocular surface lesions
url http://clinopht.com/upload/iblock/738/738db6bee97dcbf57b73098640df8c12.pdf
work_keys_str_mv AT vdyartsev topicalapplicationofheparinforthecorrectionofocularsurfacelesions