Fully human monoclonal antibodies against Ebola virus possess complete protection in a hamster model

Fully human monoclonal antibodies against Ebola virus possess complete protection in a hamster model

Ebola disease is a lethal viral hemorrhagic fever caused by ebolaviruses within the Filoviridae family with mortality rates of up to 90%. Monoclonal antibody (mAb) based therapies have shown great potential for the treatment of EVD. However, the potential emerging ebolavirus isolates and the negativ...

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Bibliographic Details
Main Authors: Wujian Li, Wanying Yang, Xueqin Liu, Wujie Zhou, Shen Wang, Zhenshan Wang, Yongkun Zhao, Na Feng, Tiecheng Wang, Meng Wu, Liangpeng Ge, Xianzhu Xia, Feihu Yan
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Ebola virus disease
Ebola virus
neutralizing antibodies
fully human antibody
transgenic mice
surrogate model
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2392651
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