Related factors of anemia in maintenance hemodialysis patients
Objective To investigate the target achievements of hemoglobin in maintenance hemodialysis（MHD） patients and related influencing factors in our center.Methods The study focused on the patients with end stage renal disease who had done hemodialysis more than 3 months in our hospital.We collected the...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2016-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57917055&Fpath=home&index=0 |
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| Summary: | Objective To investigate the target achievements of hemoglobin in maintenance hemodialysis（MHD） patients and related influencing factors in our center.Methods The study focused on the patients with end stage renal disease who had done hemodialysis more than 3 months in our hospital.We collected the information of age,sex,primary disease,weight,hemodialysis duration,hemodialysis frequency,appendix medicines and the examination records of ferritin,albumin,blood urine nitrogen,serum creatinine from January 1,2014 to January 1,2015.Then we classified the patients into different groups according to hemoglobin（Hb） level,with the chi-square test to compare the Hb levels,usage condition of erythropoietin and ferralia among these groups.Results（1） 257 MHD patients were involved in this research with the level of Hb ≥110 g/L as the target value.123 patients reached the target level,accounting for 46.7%,and 134 patients did not reach the target level,accounting for 53.3%.The target rate of Hb level was similar with domestic,but lower than foreign developed countries.These patients were assigned to different groups on the basis of their primary disease,and the top 5 were as follows:hypertensive kidney diseases（92 cases,35.80%）,chronic nephropathy（82 cases,31.91%）,diabetic kidney diseases（40,15.56%）,polycystic kidney（7,2.72%）,gout（6,2.33%）.The prevalence of anemia among these primary diseases showed significant difference（P = 0.042<0.05）.（2） The patients were classified by Hb levels.The dose of EPO[（60.54 + 50.4） IU·kg<sup>-1</sup>·W<sup>-1</sup>vs.（136.51+36.32） IU·kg<sup>-1</sup>·W<sup>-1</sup>,P<0.001]and intravenous iron[（139.01 ± 52.08） mg vs.（150 ± 78.59） mg,P<0.001) in Hb<110 g/L group were lower than in Hb ≥110 group.However,there were no statistically significant differences in age,weight,hemodialysis duration,ferritin,albumin,serum uric acid,serum creatinine between Hb<110 g/L group and Hb ≥110 group.The patients were classified by the dose of ferralia.There was no obvious difference in Hb levels between intravenous and oral groups.（3） The correlation analysis showed that the Hb level was associated with the doses of EPO（r= 0.849,P<0.01） and ferralia（r= 0.196,P<0.01）.Conclusions（1） These data showed that the standard rate of anemia treatment was 46.7%in our hemodialysis center,similar to domestic,but lower than foreign developed countries.（2） In the MHD patients given EPO,the Hb level and Hb standard rate were higher.（3） Among MHD patients using ferralia,the standard rate of Hb was higher than in those unused.And there was no obvious difference between intravenous and oral ferralia（4） The level of Hb was positively related with EPO doses and the use of ferralia. |
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| ISSN: | 1671-2390 |