WNT3A promotes the cementogenic differentiation of dental pulp stem cells through the FOXO1 signaling pathway

WNT3A promotes the cementogenic differentiation of dental pulp stem cells through the FOXO1 signaling pathway

Abstract Background Dental pulp stem cells (DPSCs) possess capability of multidirectional differentiation, and their cementogenic differentiation potential enables them to participate in cementum repair and regeneration. The molecular mechanisms underlying cementogenic differentiation of DPSCs remai...

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Main Authors: Dongmei Cheng, Yang Bao, Xue Wang, Haidong Xiang, Tianyuan Guo, Yong Du, Zhiyong Zhang, Han Guo
Format: Article
Language:English
Published: BMC 2025-02-01
Series:European Journal of Medical Research
Subjects:
WNT3A
FOXO1
Cementogenic differentiation
Dental pulp stem cells
Apoptosis
Online Access:https://doi.org/10.1186/s40001-024-02259-8
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