Arrhythmias Following Patent Foramen Ovale Closure: An Unsolved Enigma
Patent foramen ovale (PFO) closure has proven to be an effective method of reducing the risk of recurrent stroke in patients with embolic stroke of unknown origin (ESUS). One of the most recognized post-procedural complications is the de novo occurrence of supraventricular arrhythmias, mainly atrial...
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MDPI AG
2024-12-01
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| author | Aikaterini-Eleftheria Karanikola Stergios Soulaidopoulos Ioannis Leontsinis Eirini Dri Marios Sagris Athanasios Kordalis Konstantinos Aznaouridis Dimitrios Tsiachris Konstantinos Tsioufis |
| author_facet | Aikaterini-Eleftheria Karanikola Stergios Soulaidopoulos Ioannis Leontsinis Eirini Dri Marios Sagris Athanasios Kordalis Konstantinos Aznaouridis Dimitrios Tsiachris Konstantinos Tsioufis |
| author_sort | Aikaterini-Eleftheria Karanikola |
| collection | DOAJ |
| description | Patent foramen ovale (PFO) closure has proven to be an effective method of reducing the risk of recurrent stroke in patients with embolic stroke of unknown origin (ESUS). One of the most recognized post-procedural complications is the de novo occurrence of supraventricular arrhythmias, mainly atrial fibrillation, in the first three months following PFO closure. Earlier studies reported the incidence to be around 3.4–7%; however, this percentage has risen in recent studies up to 21%. The pathogenesis behind this type of arrhythmia is complex and not clearly understood, although it seems that direct effects of the device on the atria, as well as an inflammatory response, are the two most prevalent mechanisms. Management of this complication might be challenging given the heterogenicity of patient characteristics, so an individualized approach is most wisely followed. This review aims to present the current data on the incidence, pathogenesis and therapeutic strategies behind this rather common concern in an era of increasing transcatheter interventions for PFO. |
| format | Article |
| id | doaj-art-8eb22385fcb84d54ab64a85c9a03ad0d |
| institution | Kabale University |
| issn | 2075-1729 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj-art-8eb22385fcb84d54ab64a85c9a03ad0d2024-12-27T14:36:01ZengMDPI AGLife2075-17292024-12-011412159010.3390/life14121590Arrhythmias Following Patent Foramen Ovale Closure: An Unsolved EnigmaAikaterini-Eleftheria Karanikola0Stergios Soulaidopoulos1Ioannis Leontsinis2Eirini Dri3Marios Sagris4Athanasios Kordalis5Konstantinos Aznaouridis6Dimitrios Tsiachris7Konstantinos Tsioufis8First Department of Cardiology, Hippokration Hospital, Athens Medical School, National and Kapodistrian University of Athens, Vas. Sofias 114, 11527 Athens, GreeceFirst Department of Cardiology, Hippokration Hospital, Athens Medical School, National and Kapodistrian University of Athens, Vas. Sofias 114, 11527 Athens, GreeceFirst Department of Cardiology, Hippokration Hospital, Athens Medical School, National and Kapodistrian University of Athens, Vas. Sofias 114, 11527 Athens, GreeceFirst Department of Cardiology, Hippokration Hospital, Athens Medical School, National and Kapodistrian University of Athens, Vas. Sofias 114, 11527 Athens, GreeceFirst Department of Cardiology, Hippokration Hospital, Athens Medical School, National and Kapodistrian University of Athens, Vas. Sofias 114, 11527 Athens, GreeceFirst Department of Cardiology, Hippokration Hospital, Athens Medical School, National and Kapodistrian University of Athens, Vas. Sofias 114, 11527 Athens, GreeceFirst Department of Cardiology, Hippokration Hospital, Athens Medical School, National and Kapodistrian University of Athens, Vas. Sofias 114, 11527 Athens, GreeceFirst Department of Cardiology, Hippokration Hospital, Athens Medical School, National and Kapodistrian University of Athens, Vas. Sofias 114, 11527 Athens, GreeceFirst Department of Cardiology, Hippokration Hospital, Athens Medical School, National and Kapodistrian University of Athens, Vas. Sofias 114, 11527 Athens, GreecePatent foramen ovale (PFO) closure has proven to be an effective method of reducing the risk of recurrent stroke in patients with embolic stroke of unknown origin (ESUS). One of the most recognized post-procedural complications is the de novo occurrence of supraventricular arrhythmias, mainly atrial fibrillation, in the first three months following PFO closure. Earlier studies reported the incidence to be around 3.4–7%; however, this percentage has risen in recent studies up to 21%. The pathogenesis behind this type of arrhythmia is complex and not clearly understood, although it seems that direct effects of the device on the atria, as well as an inflammatory response, are the two most prevalent mechanisms. Management of this complication might be challenging given the heterogenicity of patient characteristics, so an individualized approach is most wisely followed. This review aims to present the current data on the incidence, pathogenesis and therapeutic strategies behind this rather common concern in an era of increasing transcatheter interventions for PFO.https://www.mdpi.com/2075-1729/14/12/1590patent foramen ovaleocclusionsupraventricular arrhythmiaatrial fibrillationinflammation |
| spellingShingle | Aikaterini-Eleftheria Karanikola Stergios Soulaidopoulos Ioannis Leontsinis Eirini Dri Marios Sagris Athanasios Kordalis Konstantinos Aznaouridis Dimitrios Tsiachris Konstantinos Tsioufis Arrhythmias Following Patent Foramen Ovale Closure: An Unsolved Enigma Life patent foramen ovale occlusion supraventricular arrhythmia atrial fibrillation inflammation |
| title | Arrhythmias Following Patent Foramen Ovale Closure: An Unsolved Enigma |
| title_full | Arrhythmias Following Patent Foramen Ovale Closure: An Unsolved Enigma |
| title_fullStr | Arrhythmias Following Patent Foramen Ovale Closure: An Unsolved Enigma |
| title_full_unstemmed | Arrhythmias Following Patent Foramen Ovale Closure: An Unsolved Enigma |
| title_short | Arrhythmias Following Patent Foramen Ovale Closure: An Unsolved Enigma |
| title_sort | arrhythmias following patent foramen ovale closure an unsolved enigma |
| topic | patent foramen ovale occlusion supraventricular arrhythmia atrial fibrillation inflammation |
| url | https://www.mdpi.com/2075-1729/14/12/1590 |
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