Cohort profile: the AUstralian Twin BACK pain and physical activity study (AUTBACK study)

Purpose Despite the growing evidence that physical activity and familial factors play a role in low back pain (LBP), there is a lack of robust longitudinal studies that (1) investigate the types and dosages of physical activity that are protective or harmful for LBP, (2) employ objective measures of...

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Main Authors: Manuela L Ferreira, Markus Hübscher, Ana Paula Carvalho-e-Silva, Marina B Pinheiro, Lucas Calais-Ferreira, Paulo H Ferreira
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/7/e036301.full
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author Manuela L Ferreira
Markus Hübscher
Ana Paula Carvalho-e-Silva
Marina B Pinheiro
Lucas Calais-Ferreira
Paulo H Ferreira
author_facet Manuela L Ferreira
Markus Hübscher
Ana Paula Carvalho-e-Silva
Marina B Pinheiro
Lucas Calais-Ferreira
Paulo H Ferreira
author_sort Manuela L Ferreira
collection DOAJ
description Purpose Despite the growing evidence that physical activity and familial factors play a role in low back pain (LBP), there is a lack of robust longitudinal studies that (1) investigate the types and dosages of physical activity that are protective or harmful for LBP, (2) employ objective measures of physical activity and (3) conduct appropriate adjustment for confounders. The AUstralian Twin BACK (AUTBACK) study was established to elucidate the longitudinal LBP–physical activity relationship with the benefits of controlling for familial (both genetic/nongenetic) factors that may influence physical activity engagement and LBP.Participants Participants are twins registered at Twins Research Australia (TRA), older than 18 years, with access to internet. We collected data on LBP status (weekly) and physical activity levels (monthly) for 12 months as well as a wide range of health, lifestyle and physical activity (objective, self-reported, including different types and dosages) data.Findings to date We included 401 twins, 157 being complete twin pairs (n=314). Lifetime prevalence of LBP was 85%. Participants spent 61% of their week in sedentary time and only 4% in moderate/vigorous intensity physical activity (accelerometer). So far, 168 participants (40% of the sample) have completed the 12-month follow-up. A total of 7150 weekly (LBP status) and 1763 monthly questionnaires (physical activity status) have been answered (92% response rate).Future plans The 12-month follow-up will be completed by June 2020. This cohort represents a novel and comprehensive resource for researchers in the field, and includes high-quality, and frequent data on LBP and physical activity. It allows the investigation of genetic and shared environmental factors on the LBP–physical activity relationship. The AUTBACK group has planned a number of projects, with the main one being the investigation of the influence of physical activity on recurrence of LBP. Data linkage opportunities are available, including with other studies conducted by TRA.
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spelling doaj-art-8e9229439a02456c9e66edb9b226392e2024-12-04T13:15:09ZengBMJ Publishing GroupBMJ Open2044-60552020-07-0110710.1136/bmjopen-2019-036301Cohort profile: the AUstralian Twin BACK pain and physical activity study (AUTBACK study)Manuela L Ferreira0Markus Hübscher1Ana Paula Carvalho-e-Silva2Marina B Pinheiro3Lucas Calais-Ferreira4Paulo H Ferreira5Institute of Bone and Joint Research, The Kolling Institute, University of Sydney, Sydney Medical School, Sydney, New South Wales, AustraliaNeuroscience Research Australia, Sydney, New South Wales, AustraliaMusculoskeletal Health Research Group, Faculty of Medicine and Health, School of Health Sciences, The University of Sydney, Sydney, New South Wales, AustraliaFaculty of Medicine and Health, School of Public Health, The University of Sydney, Sydney, New South Wales, AustraliaCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, AustraliaCharles Perkins Centre, Sydney Musculoskeletal Health, The University of Sydney Faculty of Medicine and Health, Sydney, New South Wales, AustraliaPurpose Despite the growing evidence that physical activity and familial factors play a role in low back pain (LBP), there is a lack of robust longitudinal studies that (1) investigate the types and dosages of physical activity that are protective or harmful for LBP, (2) employ objective measures of physical activity and (3) conduct appropriate adjustment for confounders. The AUstralian Twin BACK (AUTBACK) study was established to elucidate the longitudinal LBP–physical activity relationship with the benefits of controlling for familial (both genetic/nongenetic) factors that may influence physical activity engagement and LBP.Participants Participants are twins registered at Twins Research Australia (TRA), older than 18 years, with access to internet. We collected data on LBP status (weekly) and physical activity levels (monthly) for 12 months as well as a wide range of health, lifestyle and physical activity (objective, self-reported, including different types and dosages) data.Findings to date We included 401 twins, 157 being complete twin pairs (n=314). Lifetime prevalence of LBP was 85%. Participants spent 61% of their week in sedentary time and only 4% in moderate/vigorous intensity physical activity (accelerometer). So far, 168 participants (40% of the sample) have completed the 12-month follow-up. A total of 7150 weekly (LBP status) and 1763 monthly questionnaires (physical activity status) have been answered (92% response rate).Future plans The 12-month follow-up will be completed by June 2020. This cohort represents a novel and comprehensive resource for researchers in the field, and includes high-quality, and frequent data on LBP and physical activity. It allows the investigation of genetic and shared environmental factors on the LBP–physical activity relationship. The AUTBACK group has planned a number of projects, with the main one being the investigation of the influence of physical activity on recurrence of LBP. Data linkage opportunities are available, including with other studies conducted by TRA.https://bmjopen.bmj.com/content/10/7/e036301.full
spellingShingle Manuela L Ferreira
Markus Hübscher
Ana Paula Carvalho-e-Silva
Marina B Pinheiro
Lucas Calais-Ferreira
Paulo H Ferreira
Cohort profile: the AUstralian Twin BACK pain and physical activity study (AUTBACK study)
BMJ Open
title Cohort profile: the AUstralian Twin BACK pain and physical activity study (AUTBACK study)
title_full Cohort profile: the AUstralian Twin BACK pain and physical activity study (AUTBACK study)
title_fullStr Cohort profile: the AUstralian Twin BACK pain and physical activity study (AUTBACK study)
title_full_unstemmed Cohort profile: the AUstralian Twin BACK pain and physical activity study (AUTBACK study)
title_short Cohort profile: the AUstralian Twin BACK pain and physical activity study (AUTBACK study)
title_sort cohort profile the australian twin back pain and physical activity study autback study
url https://bmjopen.bmj.com/content/10/7/e036301.full
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