The T‐Type Calcium Channel CACNA1H is Required for Smooth Muscle Cytoskeletal Organization During Tracheal Tubulogenesis

The T‐Type Calcium Channel CACNA1H is Required for Smooth Muscle Cytoskeletal Organization During Tracheal Tubulogenesis

Abstract Abnormalities of tracheal smooth muscle (SM) formation are associated with several clinical disorders including tracheal stenosis and tracheomalacia. However, the cellular and molecular mechanisms underlying tracheal SM formation remain poorly understood. Here, it is shown that the T‐type c...

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Main Authors: Ziying Liu, Chunyan Lu, Li Ma, Changjiang Li, Haiyun Luo, Yiqi Liu, Xinyuan Liu, Haiqing Li, Yachao Cui, Jiahang Zeng, Natalia Bottasso‐Arias, Debora Sinner, Le Li, Jian Wang, Didier Y. R. Stainier, Wenguang Yin
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
Cacna1h
cytoskeleton
RhoA
smooth muscle
tracheal stenosis
Online Access:https://doi.org/10.1002/advs.202308622
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