FREQUENCIES OF POLYMORPHISMS IN THE CYTOCHROME’S P450 GENES OF WARFARIN TRANSFORMATION IN A EUROPEAN POPULATION OF EASTERN SIBERIA

FREQUENCIES OF POLYMORPHISMS IN THE CYTOCHROME’S P450 GENES OF WARFARIN TRANSFORMATION IN A EUROPEAN POPULATION OF EASTERN SIBERIA

Background. Genotypes of the cytochrome p450 isoform (CYP2C9 and CYP4F2) determine warfarin dose requirements. Frequencies of risk alleles and genotypes of CYP2C9 and CYP4F2 gene vary in different races and ethnic groups.Aim. This study analyzed the frequencies of *2, *3 alleles of CYP2C9 gene and t...

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Main Authors: T. A. Bairova, E. A. Novikova, F. I. Belyalov, E. A. Shchedreeva, K. D. Ievleva, O. V. Kalyuzhnaya, O. A. Ershova, V. G. Pustozerov, O. A. Kovaleva, I. V. Rasputina, I. A. Noskova, T. V. Batogova, O. V. Kuznetsova, O. Yu. Bogoslova, S. I. Kolesnikov
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2018-09-01
Series:Acta Biomedica Scientifica
Subjects:
cyp2c9
cyp4f2
Online Access:https://www.actabiomedica.ru/jour/article/view/705
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