How has the field of immunogenic cell death in breast cancer evolved and impacted clinical practice over the past eleven years?

This study elucidates the research landscape of immunogenic cell death (ICD) in breast cancer through a bibliometric analysis of 457 Web of Science articles. Contributions from China and the USA are particularly prominent, with notable international collaborations. Core journals such as Biomaterials...

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Main Authors: Yu-Long Deng, Bang-Teng Chi, Shang-Yi Lu, Dan-Dan Xiong, Rong-Quan He, Di-Yuan Qin, Wan-Ying Huang, Xia Yang, Gang Chen, Wei Peng, Jiayuan Luo
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Human Vaccines & Immunotherapeutics
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Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2025.2505349
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author Yu-Long Deng
Bang-Teng Chi
Shang-Yi Lu
Dan-Dan Xiong
Rong-Quan He
Di-Yuan Qin
Wan-Ying Huang
Xia Yang
Gang Chen
Wei Peng
Jiayuan Luo
author_facet Yu-Long Deng
Bang-Teng Chi
Shang-Yi Lu
Dan-Dan Xiong
Rong-Quan He
Di-Yuan Qin
Wan-Ying Huang
Xia Yang
Gang Chen
Wei Peng
Jiayuan Luo
author_sort Yu-Long Deng
collection DOAJ
description This study elucidates the research landscape of immunogenic cell death (ICD) in breast cancer through a bibliometric analysis of 457 Web of Science articles. Contributions from China and the USA are particularly prominent, with notable international collaborations. Core journals such as Biomaterials published influential studies, while researchers like Huang Y made impactful contributions. High-frequency keyword analysis identified key research hotspots, including immunotherapy, the tumor microenvironment, and nanomedicine. The integration of chemotherapy with immunotherapy and the identification of key proteins have driven recent advancements. Fundamental research on immunotherapy, photodynamic therapy (PDT), and triple-negative breast cancer (TNBC) points to future trends and potential breakthroughs. This study offers a strategic overview of ICD in breast cancer, providing insights into clinical practice and guiding future research in the field.
format Article
id doaj-art-8e5843a18ffe4d7abceec4b8b2952b5c
institution Kabale University
issn 2164-5515
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language English
publishDate 2025-12-01
publisher Taylor & Francis Group
record_format Article
series Human Vaccines & Immunotherapeutics
spelling doaj-art-8e5843a18ffe4d7abceec4b8b2952b5c2025-08-20T03:48:19ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2025-12-0121110.1080/21645515.2025.2505349How has the field of immunogenic cell death in breast cancer evolved and impacted clinical practice over the past eleven years?Yu-Long Deng0Bang-Teng Chi1Shang-Yi Lu2Dan-Dan Xiong3Rong-Quan He4Di-Yuan Qin5Wan-Ying Huang6Xia Yang7Gang Chen8Wei Peng9Jiayuan Luo10Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. ChinaDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. ChinaDepartment of Hepatological and Gland Surgery, Wuzhou Gongren Hospital/The Seventh Affiliated Hospital of Guangxi Medical University, Wuzhou, P. R. ChinaDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. ChinaDepartment of Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. ChinaDepartment of Computer Science and Technology, School of Computer and Electronic Information, Guangxi University, Nanning, P. R. ChinaDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. ChinaDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. ChinaDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. ChinaDepartment of Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. ChinaDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. ChinaThis study elucidates the research landscape of immunogenic cell death (ICD) in breast cancer through a bibliometric analysis of 457 Web of Science articles. Contributions from China and the USA are particularly prominent, with notable international collaborations. Core journals such as Biomaterials published influential studies, while researchers like Huang Y made impactful contributions. High-frequency keyword analysis identified key research hotspots, including immunotherapy, the tumor microenvironment, and nanomedicine. The integration of chemotherapy with immunotherapy and the identification of key proteins have driven recent advancements. Fundamental research on immunotherapy, photodynamic therapy (PDT), and triple-negative breast cancer (TNBC) points to future trends and potential breakthroughs. This study offers a strategic overview of ICD in breast cancer, providing insights into clinical practice and guiding future research in the field.https://www.tandfonline.com/doi/10.1080/21645515.2025.2505349Breast cancerimmunogenic cell deathbibliometricimmunotherapyclinical practice
spellingShingle Yu-Long Deng
Bang-Teng Chi
Shang-Yi Lu
Dan-Dan Xiong
Rong-Quan He
Di-Yuan Qin
Wan-Ying Huang
Xia Yang
Gang Chen
Wei Peng
Jiayuan Luo
How has the field of immunogenic cell death in breast cancer evolved and impacted clinical practice over the past eleven years?
Human Vaccines & Immunotherapeutics
Breast cancer
immunogenic cell death
bibliometric
immunotherapy
clinical practice
title How has the field of immunogenic cell death in breast cancer evolved and impacted clinical practice over the past eleven years?
title_full How has the field of immunogenic cell death in breast cancer evolved and impacted clinical practice over the past eleven years?
title_fullStr How has the field of immunogenic cell death in breast cancer evolved and impacted clinical practice over the past eleven years?
title_full_unstemmed How has the field of immunogenic cell death in breast cancer evolved and impacted clinical practice over the past eleven years?
title_short How has the field of immunogenic cell death in breast cancer evolved and impacted clinical practice over the past eleven years?
title_sort how has the field of immunogenic cell death in breast cancer evolved and impacted clinical practice over the past eleven years
topic Breast cancer
immunogenic cell death
bibliometric
immunotherapy
clinical practice
url https://www.tandfonline.com/doi/10.1080/21645515.2025.2505349
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