Enhancement structural and signaling microenvironment of artificial tumor extracellular matrix for enhanced drug screening

Enhancement structural and signaling microenvironment of artificial tumor extracellular matrix for enhanced drug screening

Bioscaffolds with characteristics of the tumor microenvironment is an important substrate to support the formation of multicellular tumor spheroids (MCTS). Conventional biomaterials promote MCTS formation using tumor extracellular matrix (ECM) components and exogenous growth factors, but lack indivi...

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Bibliographic Details
Main Authors: Xingxing Liu, Yueying Ren, Sijia Fu, Yongjie Jiao, Xinan Chen, Fujun Wang, Lu Wang, Mengbo Hu, Chaojing Li
Format: Article
Language:English
Published: SAGE Publishing 2024-11-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314241299941
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