Acute Cytomegalovirus infection as a cause of venous thromboembolism

Acute Human Cytomegalovirus (HCMV) Infection  is an unusual cause of venous thromboembolism, a potentially life-threatening condition. Thrombus formation can occur at the onset of the disease or later during recovery and may also occur in the absence of acute HCMV hepatitis. It is likely due to both...

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Main Authors: Raffaella Lissandrin, Francesco Mojoli, Fausto Baldanti, Enrico Brunetti, Michela Pascarella, Maria Teresa Giordani, Francesca Rinaldi
Format: Article
Language:English
Published: PAGEPress Publications 2014-05-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
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Online Access:http://www.mjhid.org/index.php/mjhid/article/view/1402
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author Raffaella Lissandrin
Francesco Mojoli
Fausto Baldanti
Enrico Brunetti
Michela Pascarella
Maria Teresa Giordani
Francesca Rinaldi
author_facet Raffaella Lissandrin
Francesco Mojoli
Fausto Baldanti
Enrico Brunetti
Michela Pascarella
Maria Teresa Giordani
Francesca Rinaldi
author_sort Raffaella Lissandrin
collection DOAJ
description Acute Human Cytomegalovirus (HCMV) Infection  is an unusual cause of venous thromboembolism, a potentially life-threatening condition. Thrombus formation can occur at the onset of the disease or later during recovery and may also occur in the absence of acute HCMV hepatitis. It is likely due to both vascular endothelium damage caused by HCMV and impairment of the clotting balance caused by the virus itself. Here we report on two immunocompetent women with splanchnic thrombosis that occurred during the course of acute HCMV infection. Although the prevalence of venous thrombosis in patients with acute HCMV infection is unknown, physicians should be aware of its occurrence, particularly in immune-competent patients presenting with fever and unexplained abdominal pain referred to the splanchnic region.
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series Mediterranean Journal of Hematology and Infectious Diseases
spelling doaj-art-8e15d934ce914d208ba7d5be95ba61b22025-01-02T01:58:19ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-05-0161e2014041e201404110.4084/mjhid.2014.0411162Acute Cytomegalovirus infection as a cause of venous thromboembolismRaffaella Lissandrin0Francesco Mojoli1Fausto Baldanti2Enrico Brunetti3Michela Pascarella4Maria Teresa Giordani5Francesca Rinaldi6Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, via Brambilla 74, 27100 Pavia, Italy.Department of Infectious Diseases, IRCCS San Matteo Hospital Foundation, University of Pavia, Viale Golgi 19, 27100 Pavia, ItalyClinical-Surgical, Diagnostic and Pediatric Sciences Department, Section of Anesthesia and Intensive Care 1, University of Pavia, IRCCS San Matteo Hospital Foundation, Viale Golgi 19, 27100 Pavia, ItalyMolecular Virology Unit, Virology and Microbiology Department, IRCCS San Matteo Hospital Foundation, Viale Golgi 19, 27100 Pavia, ItalyDepartment of Infectious Diseases, , IRCCS San Matteo Hospital Foundation, University of Pavia, Viale Golgi 19, 27100 Pavia, ItalyMicrobiology and Virology Service, San Bortolo Hospital, Viale Rodolfi 37, 36100 Vicenza, ItalyInfectious and Tropical Diseases Unit, San Bortolo Hospital, Viale Rodolfi 37, 36100 Vicenza, ItalyDepartment of Infectious Diseases, , IRCCS San Matteo Hospital Foundation, University of Pavia, Viale Golgi 19, 27100 Pavia, ItalyAcute Human Cytomegalovirus (HCMV) Infection  is an unusual cause of venous thromboembolism, a potentially life-threatening condition. Thrombus formation can occur at the onset of the disease or later during recovery and may also occur in the absence of acute HCMV hepatitis. It is likely due to both vascular endothelium damage caused by HCMV and impairment of the clotting balance caused by the virus itself. Here we report on two immunocompetent women with splanchnic thrombosis that occurred during the course of acute HCMV infection. Although the prevalence of venous thrombosis in patients with acute HCMV infection is unknown, physicians should be aware of its occurrence, particularly in immune-competent patients presenting with fever and unexplained abdominal pain referred to the splanchnic region.http://www.mjhid.org/index.php/mjhid/article/view/1402HCMV , portal vein thrombosis, ultrasound, immunocompetent host
spellingShingle Raffaella Lissandrin
Francesco Mojoli
Fausto Baldanti
Enrico Brunetti
Michela Pascarella
Maria Teresa Giordani
Francesca Rinaldi
Acute Cytomegalovirus infection as a cause of venous thromboembolism
Mediterranean Journal of Hematology and Infectious Diseases
HCMV , portal vein thrombosis, ultrasound, immunocompetent host
title Acute Cytomegalovirus infection as a cause of venous thromboembolism
title_full Acute Cytomegalovirus infection as a cause of venous thromboembolism
title_fullStr Acute Cytomegalovirus infection as a cause of venous thromboembolism
title_full_unstemmed Acute Cytomegalovirus infection as a cause of venous thromboembolism
title_short Acute Cytomegalovirus infection as a cause of venous thromboembolism
title_sort acute cytomegalovirus infection as a cause of venous thromboembolism
topic HCMV , portal vein thrombosis, ultrasound, immunocompetent host
url http://www.mjhid.org/index.php/mjhid/article/view/1402
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