Insight into the natural regulatory mechanisms and clinical applications of the CRISPR-Cas system

Insight into the natural regulatory mechanisms and clinical applications of the CRISPR-Cas system

CRISPR-Cas, the adaptive immune system exclusive to prokaryotes, confers resistance against foreign mobile genetic elements. The CRISPR-Cas system is now being exploited by scientists in a diverse range of genome editing applications. CRISPR-Cas systems can be categorized into six different types ba...

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Bibliographic Details
Main Authors: Hui Cheng, Haoyue Deng, Dongdao Ma, Mengyuan Gao, Zhihan Zhou, Heng Li, Shejuan Liu, Tieshan Teng
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
Subjects:
CRISPR-Cas
Genome editing
Regulatory mechanism
Clinical applications
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024155697
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