Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies

Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies

BackgroundHyperuricemia is associated with several metabolic and cardiovascular disorders, and traditional treatments, such as xanthine oxidase (XO) inhibitors, often have limitations, such as severe hypersensitivity reactions or ineffectiveness in achieving target serum urate levels in some patient...

Full description

Saved in:

Bibliographic Details
Main Authors:	Francesco Di Pierro, Fazle Rabbani, Meherullah Tareen, Roohi Nigar, Amjad Khan, Nicola Zerbinati, Maria L. Tanda, Massimiliano Cazzaniga, Alexander Bertuccioli, Paolo Falasca, Gabriele Damiani, Nicola Villanova
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Series:	Frontiers in Nutrition
Subjects:	hyperuricemia cardiovascular disease Quercetin Phytosome™ Quevir® quercetin metabolic health
Online Access:	https://www.frontiersin.org/articles/10.3389/fnut.2025.1519459/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Phytosome-Enhanced Secondary Metabolites for Improved Anticancer Efficacy: Mechanisms and Bioavailability Review
by: Mardiana L, et al.
Published: (2025-01-01)

Curcumin phytosomal softgel formulation: Development, optimization and physicochemical characterization
by: Allam Ahmed N., et al.
Published: (2015-09-01)

Phytosomes – an Effective Drug-Delivery System. Development, Technology, Application.
by: I.A. Khabarov, et al.
Published: (2024-12-01)

Phytosomes Loaded with Mastoparan-M Represent a Novel Strategy for Breast Cancer Treatment
by: Zhao H, et al.
Published: (2025-01-01)

Influence of plasma on the physical properties of ointments with quercetin
by: Szulc-Musioł Beata, et al.
Published: (2017-12-01)

The Role of Quercetin and Exercise in Modulating Apoptosis and Cardiomyopathy via PI3K/AKT/FOXO3 Pathways in Diabetic Obese Rats
by: Mojdeh Khajehlandi, et al.
Published: (2024-09-01)

Does quercetin affect tendon healing? An experimental study in a rat model of Achilles tendon injury
by: Ahmet Yurteri, et al.
Published: (2025-02-01)

Chemical characterization of fruits of Garcinia brasiliensis Mart.
by: Caroline Woelffel Silva, et al.
Published: (2025-02-01)

PYTHON INTERFACE DESIGN FOR MICROPHOTOGRAPHY ANALYSIS:APPLICATION TO EVALUATE THE HEMORHEOLOGICAL ACTIVITY OF QUERCETIN
by: P.Buszniez, et al.
Published: (2024-12-01)

Preparation and physicochemical/antimicrobial characteristics of asparagus cellulose films containing quercetin
by: Tao Jin, et al.
Published: (2021-03-01)

Improving fertilization rates in IVF using rutin and quercetin in preculture medium or through oral administration
by: Hiromitsu Tanaka, et al.
Published: (2025-01-01)

The effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity
by: İhsan Kısadere, et al.

Quercetin triggers cell apoptosis-associated ROS-mediated cell death and induces S and G2/M-phase cell cycle arrest in KON oral cancer cells
by: Sukannika Tubtimsri, et al.
Published: (2025-01-01)

Effect of quercetin on the transport of ritonavir to the central nervous system in vitro and in vivo
by: Liang Gongwen, et al.
Published: (2016-03-01)

Quercetin nanoparticles as a therapeutic approach: pharmacological actions and potential applications in therapy
by: Reham Farouk El-Sayed Baiomy
Published: (2024-12-01)

Enhanced bioavailability of Quercetin-loaded niosomal in situ gel for the management of Parkinson’s disease
by: Abhishek A. Revankar, et al.
Published: (2025-01-01)

De novo biosynthesis of quercetin in Yarrowia Lipolytica through systematic metabolic engineering for enhanced yield
by: Yuxing Dong, et al.
Published: (2025-01-01)

Enhanced hydrogel loading of quercetin-loaded hollow mesoporous cerium dioxide nanoparticles for skin flap survival
by: Xiangjun Liu, et al.
Published: (2025-02-01)

Construction of nanodelivery system based on the interaction mechanism between ultrasound–treated soybean whey protein and quercetin: structure, physicochemical stability and bioaccessibility
by: Xinru Cao, et al.
Published: (2025-01-01)

Self-microemulsifying drug delivery systems of Moringa oleifera extract for enhanced dissolution of kaempferol and quercetin
by: Sermkaew Namfa, et al.
Published: (2020-03-01)

Pulmonary prophylactic impact of melatonin and/or quercetin: A novel therapy for inflammatory hypoxic stress in rats
by: Al-Rasheed Nouf M., et al.
Published: (2017-03-01)

Green synthesis of silver and gold nanoparticles using quercetin extracted from Arctium lappa by HPLC, Characterization and Estimation of antioxidant activity
by: Mahmood Zaki Lafta, et al.
Published: (2025-01-01)

The Role of Quercetin, a Flavonoid in the Management of Pathogenesis Through Regulation of Oxidative Stress, Inflammation, and Biological Activities
by: Hajed Obaid A. Alharbi, et al.
Published: (2025-01-01)

(−)-Epigallocatechin-3-Gallate and Quercetin Inhibit Quiescin Sulfhydryl Oxidase 1 Secretion from Hepatocellular Carcinoma Cells
by: Lumin Yang, et al.
Published: (2025-01-01)

Study of vascular endothelial dysfunction in children with beta-thalassemia major before and after quercetin therapy
by: Fatma Al Zahraa Sherai, et al.
Published: (2025-02-01)

Collaborative Effects of Caloric Restriction and Quercetin on Age-related Oxidative Stress Reduction through NQO1/Sirt1 Gene Regulation
by: Fereshte Ghorbani, et al.
Published: (2024-12-01)

Quercetin, a natural antioxidant compound for the treatment of oral cancer therapy
by: Sureshkumar Selvaraj, et al.
Published: (2024-06-01)

Resveratrol, Piceatannol, Curcumin, and Quercetin as Therapeutic Targets in Gastric Cancer—Mechanisms and Clinical Implications for Natural Products
by: Paulina Warias, et al.
Published: (2024-12-01)

SYNERGISTIC EFFECT OF QUERCETIN AND EPIGALLOCATECHIN-3-GALLATE AS AGENTS TO PREVENT CONNECTIVE TISSUE DISINTEGRATION IN THE PERIODONTIUM OF RATS UNDER SYSTEMIC AND LOCAL ADMINISTRATION OF LIPOPOLISACCHARIDE OF SALMONELLA TYPHI
by: A.M. Yelins’ka, et al.
Published: (2019-12-01)

Protective mechanism of quercetin compounds against acrylamide-induced hepatotoxicity
by: Linzi Li, et al.
Published: (2024-01-01)

Quercetin attenuates cisplatin-induced fatigue through mechanisms associated with the regulation of the HPA axis and MCP-1 signaling
by: Cheng-Hung Chuang, et al.
Published: (2025-01-01)

Multi-targeted nanogel drug delivery system alleviates neuroinflammation and promotes spinal cord injury repair
by: Penghui Wang, et al.
Published: (2025-04-01)

Role of Quercetin in Diabetic Cardiomyopathy
by: Nor Hidayah Mustafa, et al.
Published: (2024-12-01)

Evaluation of Quercetin Content, Colour and Selected Physico-Chemical Quality Parameters of Croatian Blackberry Wines
by: Klarić Daniela Amidžić, et al.
Published: (2017-03-01)

Quercetin improves diabetic kidney disease by inhibiting ferroptosis and regulating the Nrf2 in streptozotocin-induced diabetic rats
by: Lei Zhang, et al.
Published: (2024-12-01)

THE EFFECT OF QUERCETIN ON MORPHOLOGICAL AND BIOCHEMICAL CHANGES IN RAT LIVER UNDER 270TH DAY CENTRAL DEPRIVATION OF LUTEINIZING HORMONE SYNTHESIS
by: M.V. Rud, et al.
Published: (2022-04-01)

Multimodal lung cancer theranostics via manganese phosphate/quercetin particle
by: Chong Qiu, et al.
Published: (2025-02-01)

Effect of Quercetin on Bone Mineral Status and Markers of Bone Turnover in Retinoic Acid-Induced Osteoporosis
by: Oršolić Nada, et al.
Published: (2018-06-01)

The impact of prolonged blockade of the releasing hormone on alterations in cardiac macrophage polarisation subsequent to quercetin administration in rats
by: T.A. Voroshylova, et al.
Published: (2024-12-01)

Exploring the mechanism of action of Rosa roxburghii Tratt quercetin in ameliorating type 2 diabetes in mice based on the intestinal microbiome and metabolomics
by: Ziyi Zhao, et al.
Published: (2025-01-01)