Early gestation heat stress influences fetal biomarkers indicative of maternal cortisol transfer in pigs

Early gestation heat stress influences fetal biomarkers indicative of maternal cortisol transfer in pigs

Abstract In utero heat stress (IUHS) alters hypothalamic-pituitary-adrenal (HPA) axis development in pigs; however, the mechanisms mediating this effect remain unclear. This study aimed to evaluate cortisol transfer dynamics from the heat-stressed (HS) dam to the IUHS conceptus during early gestatio...

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Bibliographic Details
Main Authors: MaryKate H. Byrd, L. Kirsten Senn, Alex Pasternak, Kara R. Stewart, Jay S. Johnson
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
11β-HSD2
Fetal cortisol
Fetal cortisone
In utero heat stress
Maternal cortisol
Online Access:https://doi.org/10.1038/s41598-025-12698-w
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