Comparison of bispectral index-guided endoscopic ultrasonography with continuous versus intermittent infusion of propofol: a retrospective study in Japan
Background/Aims This study aimed to evaluate the safety and efficacy of continuous propofol infusion for anesthesia during endoscopic ultrasonography (EUS). Methods A total of 427 consecutive patients who underwent EUS between May 2018 and February 2019 were enrolled in this study. The patients were...
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Korean Society of Gastrointestinal Endoscopy
2024-11-01
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| Series: | Clinical Endoscopy |
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| Online Access: | http://www.e-ce.org/upload/pdf/ce-2024-019.pdf |
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| author | Ayana Okamoto Ken Kamata Tomohiro Yamazaki Shunsuke Omoto Kosuke Minaga Mamoru Takenaka Masatoshi Kudo |
| author_facet | Ayana Okamoto Ken Kamata Tomohiro Yamazaki Shunsuke Omoto Kosuke Minaga Mamoru Takenaka Masatoshi Kudo |
| author_sort | Ayana Okamoto |
| collection | DOAJ |
| description | Background/Aims This study aimed to evaluate the safety and efficacy of continuous propofol infusion for anesthesia during endoscopic ultrasonography (EUS). Methods A total of 427 consecutive patients who underwent EUS between May 2018 and February 2019 were enrolled in this study. The patients were divided into two propofol infusion groups: continuous (n=207) and intermittent (n=220). The following parameters were compared: (1) propofol dose, (2) respiratory and circulatory depression, (3) body movement requiring discontinuation of the examination, (4) awakening score, and (5) patient satisfaction. Results The median total maintenance dose of propofol was significantly higher in the continuous group than in the intermittent group (160.0 mg vs. 130.0 mg, respectively); however, the reduction in SpO2 was significantly lower in the continuous group (2.9% vs. 13.2%). Body movements occurred less frequently in the continuous group than in the intermittent group (40.1% vs. 49.5%, respectively). The rate of complete awakening was significantly higher in the continuous group than in the intermittent group. Finally, there was a significant difference in the percentage of patients who answered “absolutely yes” when asked about receiving EUS again: 52.7% in the continuous group vs. 34.3% in the intermittent group. Conclusions Continuous infusion resulted in stable sedation and reduced propofol-associated risks. |
| format | Article |
| id | doaj-art-8d9b99a38c1e4b32acd745e81f87574f |
| institution | Kabale University |
| issn | 2234-2400 2234-2443 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Korean Society of Gastrointestinal Endoscopy |
| record_format | Article |
| series | Clinical Endoscopy |
| spelling | doaj-art-8d9b99a38c1e4b32acd745e81f87574f2024-12-03T07:42:10ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432024-11-0157681482010.5946/ce.2024.0197897Comparison of bispectral index-guided endoscopic ultrasonography with continuous versus intermittent infusion of propofol: a retrospective study in JapanAyana OkamotoKen KamataTomohiro YamazakiShunsuke OmotoKosuke MinagaMamoru TakenakaMasatoshi KudoBackground/Aims This study aimed to evaluate the safety and efficacy of continuous propofol infusion for anesthesia during endoscopic ultrasonography (EUS). Methods A total of 427 consecutive patients who underwent EUS between May 2018 and February 2019 were enrolled in this study. The patients were divided into two propofol infusion groups: continuous (n=207) and intermittent (n=220). The following parameters were compared: (1) propofol dose, (2) respiratory and circulatory depression, (3) body movement requiring discontinuation of the examination, (4) awakening score, and (5) patient satisfaction. Results The median total maintenance dose of propofol was significantly higher in the continuous group than in the intermittent group (160.0 mg vs. 130.0 mg, respectively); however, the reduction in SpO2 was significantly lower in the continuous group (2.9% vs. 13.2%). Body movements occurred less frequently in the continuous group than in the intermittent group (40.1% vs. 49.5%, respectively). The rate of complete awakening was significantly higher in the continuous group than in the intermittent group. Finally, there was a significant difference in the percentage of patients who answered “absolutely yes” when asked about receiving EUS again: 52.7% in the continuous group vs. 34.3% in the intermittent group. Conclusions Continuous infusion resulted in stable sedation and reduced propofol-associated risks.http://www.e-ce.org/upload/pdf/ce-2024-019.pdfbispectralcontinuousendosonographypropofolsedation |
| spellingShingle | Ayana Okamoto Ken Kamata Tomohiro Yamazaki Shunsuke Omoto Kosuke Minaga Mamoru Takenaka Masatoshi Kudo Comparison of bispectral index-guided endoscopic ultrasonography with continuous versus intermittent infusion of propofol: a retrospective study in Japan Clinical Endoscopy bispectral continuous endosonography propofol sedation |
| title | Comparison of bispectral index-guided endoscopic ultrasonography with continuous versus intermittent infusion of propofol: a retrospective study in Japan |
| title_full | Comparison of bispectral index-guided endoscopic ultrasonography with continuous versus intermittent infusion of propofol: a retrospective study in Japan |
| title_fullStr | Comparison of bispectral index-guided endoscopic ultrasonography with continuous versus intermittent infusion of propofol: a retrospective study in Japan |
| title_full_unstemmed | Comparison of bispectral index-guided endoscopic ultrasonography with continuous versus intermittent infusion of propofol: a retrospective study in Japan |
| title_short | Comparison of bispectral index-guided endoscopic ultrasonography with continuous versus intermittent infusion of propofol: a retrospective study in Japan |
| title_sort | comparison of bispectral index guided endoscopic ultrasonography with continuous versus intermittent infusion of propofol a retrospective study in japan |
| topic | bispectral continuous endosonography propofol sedation |
| url | http://www.e-ce.org/upload/pdf/ce-2024-019.pdf |
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