Pathogen class-specific transcriptional responses derived from PBMCs accurately discriminate between fungal, bacterial, and viral infections.

Pathogen class-specific transcriptional responses derived from PBMCs accurately discriminate between fungal, bacterial, and viral infections.

Immune responses during acute infection often contain canonical elements which are shared across the responses to an array of agents within a given pathogen class (i.e., respiratory viral infection). Identification of these shared, canonical elements across similar infections offers the potential fo...

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Bibliographic Details
Main Authors: Julie M Steinbrink, Yiling Liu, Ricardo Henao, Ephraim L Tsalik, Geoffrey S Ginsburg, Elizabeth Ramsburg, Christopher W Woods, Micah T McClain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0311007
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