Precise HER2 Protein Degradation via Peptide‐Conjugated Photodynamic Therapy for Enhanced Breast Cancer Immunotherapy

Precise HER2 Protein Degradation via Peptide‐Conjugated Photodynamic Therapy for Enhanced Breast Cancer Immunotherapy

Abstract Breast cancer, the most prevalent malignancy among women, frequently exhibits high HER2 expression, making HER2 a critical therapeutic target. Traditional treatments combining the anti‐HER2 antibody trastuzumab with immunotherapy face limitations due to toxicity and tumor microenvironment i...

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Bibliographic Details
Main Authors: Changyong Guo, Fei Gao, Guoyuan Wu, Jinqiu Li, Chunquan Sheng, Shipeng He, Honggang Hu
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
breast cancer
gelatinase responsive peptides
immune induction
photo‐controlled her2 protein degradation
photodynamic immunotherapy
Online Access:https://doi.org/10.1002/advs.202410778
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