Revealing and mitigating the inhibitory effect of serotonin on HRP-mediated protein labelling

Abstract Proximity-dependent biotinylation coupled with mass spectrometry enables the characterization of subcellular proteomes. This technique has significantly advanced neuroscience by revealing sub-synaptic protein networks, such as the synaptic cleft and post-synaptic density. Profiling proteins...

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Bibliographic Details
Main Authors: Zora Chui-Kuen Chan, Cheng Qi, Yuanhong Cai, Xin Li, Jing Ren
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-83928-w
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