Computational insights in CD58 binding to ASFV CD2v and in silico optimization of nanobody designs against the interface

Computational insights in CD58 binding to ASFV CD2v and in silico optimization of nanobody designs against the interface

Background: African swine fever (ASF) continues to hamper pork production worldwide. In addition to vaccines, there is a need to develop curative therapeutics, such as highly-specific antibodies or nanobodies, against immunogenic proteins with important functions such as the viral CD2-like protein...

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Bibliographic Details
Main Authors: Albert Neil Gura Dulay, Richelle Mae Evasco Padilla, Nyzar Mabeth Obenio Odchimar, Fredmoore Legaspi Orosco
Format: Article
Language:English
Published: Tripoli University 2025-01-01
Series:Open Veterinary Journal
Subjects:
cd2v
computational biology
site-directed mutagenesis
antiviral
asfv
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=227234
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