Creutzfeldt–Jakob disease: A case report
Creutzfeldt–Jakob Disease (CJD) is a rare, fatal neurodegenerative disorder that is caused by prion proteins. Patients often present with rapidly progressive dementia, ataxia, myoclonus, memory impairment, visual problems, and changes in personality. In this case report, we aimed to address the cour...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043324012780 |
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| author | Fahad Rasool Butt, HBSc Thanansayan Dhivagaran, HBSc Syed Naqvi, MD, FRCPC, DABR |
| author_facet | Fahad Rasool Butt, HBSc Thanansayan Dhivagaran, HBSc Syed Naqvi, MD, FRCPC, DABR |
| author_sort | Fahad Rasool Butt, HBSc |
| collection | DOAJ |
| description | Creutzfeldt–Jakob Disease (CJD) is a rare, fatal neurodegenerative disorder that is caused by prion proteins. Patients often present with rapidly progressive dementia, ataxia, myoclonus, memory impairment, visual problems, and changes in personality. In this case report, we aimed to address the course of a 62 year old female who presented with progressive decline in cognitive function and died within 6 months of presentation. The patient underwent cerebrospinal fluid testing, MRI brain, and electroencephalography during her stay in the hospital. Ultimately, an autopsy was performed, which demonstrated spongiform changes, neuronal loss, and astrogliosis, consistent with CJD. |
| format | Article |
| id | doaj-art-8c4d36ac3e36456d978ef890c2cc26c6 |
| institution | Kabale University |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-8c4d36ac3e36456d978ef890c2cc26c62024-12-18T08:47:55ZengElsevierRadiology Case Reports1930-04332025-02-0120210951098Creutzfeldt–Jakob disease: A case reportFahad Rasool Butt, HBSc0Thanansayan Dhivagaran, HBSc1Syed Naqvi, MD, FRCPC, DABR2Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, CanadaSchulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, CanadaSchulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada; Department of Medical Imaging, Western University, Windsor, Ontario, Canada; Correspondence address.Creutzfeldt–Jakob Disease (CJD) is a rare, fatal neurodegenerative disorder that is caused by prion proteins. Patients often present with rapidly progressive dementia, ataxia, myoclonus, memory impairment, visual problems, and changes in personality. In this case report, we aimed to address the course of a 62 year old female who presented with progressive decline in cognitive function and died within 6 months of presentation. The patient underwent cerebrospinal fluid testing, MRI brain, and electroencephalography during her stay in the hospital. Ultimately, an autopsy was performed, which demonstrated spongiform changes, neuronal loss, and astrogliosis, consistent with CJD.http://www.sciencedirect.com/science/article/pii/S1930043324012780Creutzfeldt–Jakob diseaseMRINeurodegenerative disorderSpongiform encephalopathyPrion diseaseRapidly progressive dementia |
| spellingShingle | Fahad Rasool Butt, HBSc Thanansayan Dhivagaran, HBSc Syed Naqvi, MD, FRCPC, DABR Creutzfeldt–Jakob disease: A case report Radiology Case Reports Creutzfeldt–Jakob disease MRI Neurodegenerative disorder Spongiform encephalopathy Prion disease Rapidly progressive dementia |
| title | Creutzfeldt–Jakob disease: A case report |
| title_full | Creutzfeldt–Jakob disease: A case report |
| title_fullStr | Creutzfeldt–Jakob disease: A case report |
| title_full_unstemmed | Creutzfeldt–Jakob disease: A case report |
| title_short | Creutzfeldt–Jakob disease: A case report |
| title_sort | creutzfeldt jakob disease a case report |
| topic | Creutzfeldt–Jakob disease MRI Neurodegenerative disorder Spongiform encephalopathy Prion disease Rapidly progressive dementia |
| url | http://www.sciencedirect.com/science/article/pii/S1930043324012780 |
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