Reconceptualizing the ventricular-arterial interaction for non-invasive damping modelling: Application in young soccer players and ballet dancers
Introduction: The left ventricle (LV) serves as the primary source of mechanical energy in circulation, subsequently converted into kinetic energy throughout the arterial system (AS). Analyzing the specific area within an LV pressure-volume (PV) loop helps characterize the function of the cardiac pu...
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Elsevier
2024-12-01
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| author | Lucía Lemes Ricardo L. Armentano Ignacio Farro Leandro J. Cymberknop |
| author_facet | Lucía Lemes Ricardo L. Armentano Ignacio Farro Leandro J. Cymberknop |
| author_sort | Lucía Lemes |
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| description | Introduction: The left ventricle (LV) serves as the primary source of mechanical energy in circulation, subsequently converted into kinetic energy throughout the arterial system (AS). Analyzing the specific area within an LV pressure-volume (PV) loop helps characterize the function of the cardiac pump. Simultaneously, the AS functions as a blood reservoir, receiving the blood ejected by the LV. The enclosed area in the AS PV-loop is linked to an energy dissipation process (where not all pressure work is regained), attributed to the viscous function of smooth muscle cells. Objective: The main objective of this work was to investigate wall energy dissipation in the vascular bed in terms of LV and AS PV-loop evaluation, to determine if different types of training could lead to differentiated levels of wall energy dissipation. The ‘coupling concept’ is proposed to be conceived from LV and AS loop energy interaction, quantified by a ‘ventricular-arterial damping factor’ (VADF). Material and Methods: Data from subjects with different kinds of training (soccer players and ballet dancers) were collected noninvasively and compared with a control group of untrained individuals to analyze the differentiating characteristics of the subjects, especially in terms of Stroke Work Dissipation (WDIS). To this end, a lumped parameters Windkessel (WK) model was proposed for the assessment of LV and AS loops, through an interactive process. Changes in wall energy dissipation were observed under training routines. Both soccer players and ballet dancers showed increased WDIS and VADF compared to the untrained individuals (p<0.05). However, elastic work (WEL), defined as the difference between LV stroke work and WDIS, was found to remain constant in ballet dancers, unlike in soccer players. Conclusion: The WK model enabled the simulation of the interaction between LV and AS based on a ventricular-arterial coupling framework. The findings suggest that higher WDIS values, together with the preservation of WEL, may indicate an enhanced protective effect by vascular smooth muscle cells and other wall components, involved in the AS dissipation phenomenon. |
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| institution | Kabale University |
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| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
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| series | Franklin Open |
| spelling | doaj-art-8c3d81cfd9e440e4bf0a256522712bc92024-12-19T11:03:32ZengElsevierFranklin Open2773-18632024-12-019100179Reconceptualizing the ventricular-arterial interaction for non-invasive damping modelling: Application in young soccer players and ballet dancersLucía Lemes0Ricardo L. Armentano1Ignacio Farro2Leandro J. Cymberknop3Departamento de Ingeniería Biológica, CENUR Litoral Norte, Universidad de la República, UruguayDepartamento de Ingeniería Biológica, CENUR Litoral Norte, Universidad de la República, Uruguay; Corresponding author.Departamento de Ingeniería Biológica, CENUR Litoral Norte, Universidad de la República, Uruguay; Servicio de Imagenología Cardíaca, Cardiocentro, Asociación Española de Montevideo, UruguayUniversidad Tecnológica Nacional, Facultad Regional Buenos Aires, Grupo de Investigación y Desarrollo en Bioingeniería (GIBIO), Buenos Aires, Argentina.Introduction: The left ventricle (LV) serves as the primary source of mechanical energy in circulation, subsequently converted into kinetic energy throughout the arterial system (AS). Analyzing the specific area within an LV pressure-volume (PV) loop helps characterize the function of the cardiac pump. Simultaneously, the AS functions as a blood reservoir, receiving the blood ejected by the LV. The enclosed area in the AS PV-loop is linked to an energy dissipation process (where not all pressure work is regained), attributed to the viscous function of smooth muscle cells. Objective: The main objective of this work was to investigate wall energy dissipation in the vascular bed in terms of LV and AS PV-loop evaluation, to determine if different types of training could lead to differentiated levels of wall energy dissipation. The ‘coupling concept’ is proposed to be conceived from LV and AS loop energy interaction, quantified by a ‘ventricular-arterial damping factor’ (VADF). Material and Methods: Data from subjects with different kinds of training (soccer players and ballet dancers) were collected noninvasively and compared with a control group of untrained individuals to analyze the differentiating characteristics of the subjects, especially in terms of Stroke Work Dissipation (WDIS). To this end, a lumped parameters Windkessel (WK) model was proposed for the assessment of LV and AS loops, through an interactive process. Changes in wall energy dissipation were observed under training routines. Both soccer players and ballet dancers showed increased WDIS and VADF compared to the untrained individuals (p<0.05). However, elastic work (WEL), defined as the difference between LV stroke work and WDIS, was found to remain constant in ballet dancers, unlike in soccer players. Conclusion: The WK model enabled the simulation of the interaction between LV and AS based on a ventricular-arterial coupling framework. The findings suggest that higher WDIS values, together with the preservation of WEL, may indicate an enhanced protective effect by vascular smooth muscle cells and other wall components, involved in the AS dissipation phenomenon.http://www.sciencedirect.com/science/article/pii/S2773186324001099Pressure-volume loopCardiovascular systemDamping factorArterial wall energy dissipationTrained individuals |
| spellingShingle | Lucía Lemes Ricardo L. Armentano Ignacio Farro Leandro J. Cymberknop Reconceptualizing the ventricular-arterial interaction for non-invasive damping modelling: Application in young soccer players and ballet dancers Franklin Open Pressure-volume loop Cardiovascular system Damping factor Arterial wall energy dissipation Trained individuals |
| title | Reconceptualizing the ventricular-arterial interaction for non-invasive damping modelling: Application in young soccer players and ballet dancers |
| title_full | Reconceptualizing the ventricular-arterial interaction for non-invasive damping modelling: Application in young soccer players and ballet dancers |
| title_fullStr | Reconceptualizing the ventricular-arterial interaction for non-invasive damping modelling: Application in young soccer players and ballet dancers |
| title_full_unstemmed | Reconceptualizing the ventricular-arterial interaction for non-invasive damping modelling: Application in young soccer players and ballet dancers |
| title_short | Reconceptualizing the ventricular-arterial interaction for non-invasive damping modelling: Application in young soccer players and ballet dancers |
| title_sort | reconceptualizing the ventricular arterial interaction for non invasive damping modelling application in young soccer players and ballet dancers |
| topic | Pressure-volume loop Cardiovascular system Damping factor Arterial wall energy dissipation Trained individuals |
| url | http://www.sciencedirect.com/science/article/pii/S2773186324001099 |
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