Validity of the scoring system for traumatic liver injury: a generalized estimating equation analysis
Purpose The scoring system for traumatic liver injury (SSTLI) was developed in 2015 to predict mortality in patients with polytraumatic liver injury. This study aimed to validate the SSTLI as a prognostic factor in patients with polytrauma and liver injury through a generalized estimating equation a...
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| Format: | Article |
| Language: | English |
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Korean Society of Traumatology
2022-03-01
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| Series: | Journal of Trauma and Injury |
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| Online Access: | http://jtraumainj.org/upload/pdf/jti-2021-0009.pdf |
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| author | Kangho Lee Dongyeon Ryu Hohyun Kim Chang Ho Jeon Jae Hun Kim Chan Yong Park Seok Ran Yeom |
| author_facet | Kangho Lee Dongyeon Ryu Hohyun Kim Chang Ho Jeon Jae Hun Kim Chan Yong Park Seok Ran Yeom |
| author_sort | Kangho Lee |
| collection | DOAJ |
| description | Purpose The scoring system for traumatic liver injury (SSTLI) was developed in 2015 to predict mortality in patients with polytraumatic liver injury. This study aimed to validate the SSTLI as a prognostic factor in patients with polytrauma and liver injury through a generalized estimating equation analysis. Methods The medical records of 521 patients with traumatic liver injury from January 2015 to December 2019 were reviewed. The primary outcome variable was in-hospital mortality. All the risk factors were analyzed using multivariate logistic regression analysis. The SSTLI has five clinical measures (age, Injury Severity Score, serum total bilirubin level, prothrombin time, and creatinine level) chosen based on their predictive power. Each measure is scored as 0–1 (age and Injury Severity Score) or 0–3 (serum total bilirubin level, prothrombin time, and creatinine level). The SSTLI score corresponds to the total points for each item (0–11 points). Results The areas under the curve of the SSTLI to predict mortality on post-traumatic days 0, 1, 3, and 5 were 0.736, 0.783, 0.830, and 0.824, respectively. A very good to excellent positive correlation was observed between the probability of mortality and the SSTLI score (γ=0.997, P<0.001). A value of 5 points was used as the threshold to distinguish low-risk (<5) from high-risk (≥5) patients. Multivariate analysis using the generalized estimating equation in the logistic regression model indicated that the SSTLI score was an independent predictor of mortality (odds ratio, 1.027; 95% confidence interval, 1.018–1.036; P<0.001). Conclusions The SSTLI was verified to predict mortality in patients with polytrauma and liver injury. A score of ≥5 on the SSTLI indicated a high-risk of post-traumatic mortality. |
| format | Article |
| id | doaj-art-8c333beae8aa48a39903d34c9e48e841 |
| institution | Kabale University |
| issn | 2799-4317 2287-1683 |
| language | English |
| publishDate | 2022-03-01 |
| publisher | Korean Society of Traumatology |
| record_format | Article |
| series | Journal of Trauma and Injury |
| spelling | doaj-art-8c333beae8aa48a39903d34c9e48e8412025-01-16T04:51:03ZengKorean Society of TraumatologyJournal of Trauma and Injury2799-43172287-16832022-03-01351253310.20408/jti.2021.00091086Validity of the scoring system for traumatic liver injury: a generalized estimating equation analysisKangho Lee0Dongyeon Ryu1Hohyun Kim2Chang Ho Jeon3Jae Hun Kim4Chan Yong Park5Seok Ran Yeom6 Department of Trauma and Surgical Critical Care, Pusan National University Hospital, Busan, Korea Department of Trauma and Surgical Critical Care, Pusan National University Hospital, Busan, Korea Department of Trauma and Surgical Critical Care, Pusan National University Hospital, Busan, Korea Department of Diagnostic Radiology, The Catholic University of Korea Eunpyeong St. Mary's Hospital, Seoul, Korea Department of Trauma and Surgical Critical Care, Pusan National University Hospital, Busan, Korea Department of Trauma Surgery, Seoul National University Hospital, Seoul, Korea Biomedical Research Institute, Pusan National University Hospital, Busan, KoreaPurpose The scoring system for traumatic liver injury (SSTLI) was developed in 2015 to predict mortality in patients with polytraumatic liver injury. This study aimed to validate the SSTLI as a prognostic factor in patients with polytrauma and liver injury through a generalized estimating equation analysis. Methods The medical records of 521 patients with traumatic liver injury from January 2015 to December 2019 were reviewed. The primary outcome variable was in-hospital mortality. All the risk factors were analyzed using multivariate logistic regression analysis. The SSTLI has five clinical measures (age, Injury Severity Score, serum total bilirubin level, prothrombin time, and creatinine level) chosen based on their predictive power. Each measure is scored as 0–1 (age and Injury Severity Score) or 0–3 (serum total bilirubin level, prothrombin time, and creatinine level). The SSTLI score corresponds to the total points for each item (0–11 points). Results The areas under the curve of the SSTLI to predict mortality on post-traumatic days 0, 1, 3, and 5 were 0.736, 0.783, 0.830, and 0.824, respectively. A very good to excellent positive correlation was observed between the probability of mortality and the SSTLI score (γ=0.997, P<0.001). A value of 5 points was used as the threshold to distinguish low-risk (<5) from high-risk (≥5) patients. Multivariate analysis using the generalized estimating equation in the logistic regression model indicated that the SSTLI score was an independent predictor of mortality (odds ratio, 1.027; 95% confidence interval, 1.018–1.036; P<0.001). Conclusions The SSTLI was verified to predict mortality in patients with polytrauma and liver injury. A score of ≥5 on the SSTLI indicated a high-risk of post-traumatic mortality.http://jtraumainj.org/upload/pdf/jti-2021-0009.pdfwounds and injurieslivertrauma severity indicesprognosis |
| spellingShingle | Kangho Lee Dongyeon Ryu Hohyun Kim Chang Ho Jeon Jae Hun Kim Chan Yong Park Seok Ran Yeom Validity of the scoring system for traumatic liver injury: a generalized estimating equation analysis Journal of Trauma and Injury wounds and injuries liver trauma severity indices prognosis |
| title | Validity of the scoring system for traumatic liver injury: a generalized estimating equation analysis |
| title_full | Validity of the scoring system for traumatic liver injury: a generalized estimating equation analysis |
| title_fullStr | Validity of the scoring system for traumatic liver injury: a generalized estimating equation analysis |
| title_full_unstemmed | Validity of the scoring system for traumatic liver injury: a generalized estimating equation analysis |
| title_short | Validity of the scoring system for traumatic liver injury: a generalized estimating equation analysis |
| title_sort | validity of the scoring system for traumatic liver injury a generalized estimating equation analysis |
| topic | wounds and injuries liver trauma severity indices prognosis |
| url | http://jtraumainj.org/upload/pdf/jti-2021-0009.pdf |
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