Cardiac-Specific Gene Expression Facilitated by an Enhanced Myosin Light Chain Promoter
Background: Adenoviral gene transfer has been shown to be effective in cardiac myocytes in vitro and in vivo. A major limitation of myocardial gene therapy is the extracardiac transgene expression. Methods: To minimize extracardiac gene expression, we have constructed a tissue-specific promoter for...
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Main Authors: | Wolfgang Boecker, Oliver Y. Bernecker, Joseph C. Wu, Xinsheng Zhu, Tomohiro Sawa, Luanda Grazette, Anthony Rosenzweig, Federica del Monte, Ulrich Schmidt, Roger J. Hajjar |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2004-04-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.1162/15353500200404103 |
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