Genetic prioritisation of candidate drug targets for glaucoma through multi-trait and multi-omics integration

Genetic prioritisation of candidate drug targets for glaucoma through multi-trait and multi-omics integration

Abstract Background Glaucoma causes permanent blindness. Current treatments have limited effectiveness, necessitating novel therapeutic strategies. We aimed to identify potential drug targets for glaucoma by integrating multi-trait and multi-omic analyses. Methods We sourced druggable gene expressio...

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Bibliographic Details
Main Authors: Jianqi Chen, Yangjiani Li, Yingting Zhu, Zhidong Li, Shitong Huang, Wenzhi Huang, Yuyao Ling, Jingying Liang, Yunxia Leng, Yehong Zhuo
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Eye and Vision
Subjects:
Druggable targets
Glaucoma
Multi-omics
Multi-traits
Online Access:https://doi.org/10.1186/s40662-025-00442-4
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