Thromboelastography for the evaluation of coagulation function in patients with hepatic echinococcosis during the perioperative period: a retrospective study
ObjectiveTo study the application of thrombolysis diagram (TEG) and routine coagulation test in the evaluation of coagulation function in patients with hepatic hydatid.MethodsThe observation group consisted of 69 cases of hydatid liver patients undergoing elective combined segmenectomy, and the cont...
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1603148/full |
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| author | Xing Zheng Li Yuan Bingxian Wang Genkui Li Jing Wang Jide A Zongzhao He |
| author_facet | Xing Zheng Li Yuan Bingxian Wang Genkui Li Jing Wang Jide A Zongzhao He |
| author_sort | Xing Zheng |
| collection | DOAJ |
| description | ObjectiveTo study the application of thrombolysis diagram (TEG) and routine coagulation test in the evaluation of coagulation function in patients with hepatic hydatid.MethodsThe observation group consisted of 69 cases of hydatid liver patients undergoing elective combined segmenectomy, and the control group consisted of 69 healthy subjects. The correlation analysis of TEG, six coagulation items and PLT in the preoperative observation group and control group was conducted. The differences of TEG, hemagglutination six and PLT between the two groups were compared. TEG and coagulation function indexes of observation group were compared at different time during perioperative period.ResultsIn the control group, The time of blood cell aggregation (K) was negatively correlated with prothrombin time (PT), fibrinogen (FIB) and platelet count(PLT); The maximum strength of blood clot (MA) was positively correlated with PT, FIB and PLT; The rate of blood cell aggregation (Angle) is positively correlated with PT, FIB and PLT; the comprehensive index of blood coagulation (CI) was positively correlated with FIB and PLT. The reaction time of blood coagulation (R) of observation group was positively correlated with PT; MA was positively correlated with PT, FIB and PLT; MA was negatively correlated with thrombin time (TT). activated partial thromboplastin time (APTT), D-dimer (DD), PLT, R value, K value, Angle, MA and CI were compared between the two groups, and the differences were statistically significant (P<0.05). Compared with T1, APTT, R value, Angle and MA in observation group were significantly decreased at T2 and T3 (P<0.05); Compared with T1, PT, TT, FIB and K values had no significant changes (P>0.05).ConclusionThe coagulation function of liver hydatid patients was relatively low during the perioperative period, TEG is more sensitive to changes in perioperative coagulation function and can comprehensively understand the patient’s coagulation state. |
| format | Article |
| id | doaj-art-8bb0cf65a48c47c2876b4758ac4f2029 |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Oncology |
| spelling | doaj-art-8bb0cf65a48c47c2876b4758ac4f20292025-08-21T05:27:15ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-08-011510.3389/fonc.2025.16031481603148Thromboelastography for the evaluation of coagulation function in patients with hepatic echinococcosis during the perioperative period: a retrospective studyXing Zheng0Li Yuan1Bingxian Wang2Genkui Li3Jing Wang4Jide A5Zongzhao He6Department of Intensive Care Unit, Qinghai Provincial People’s Hospital, Xining, ChinaDepartment of Anesthesiology, Qinghai Provincial People’s Hospital, Xining, ChinaDepartment of Intensive Care Unit, Qinghai Provincial People’s Hospital, Xining, ChinaDepartment of Radiology, Hospital of Honghe State Affiliated to Kunming Medical University, Kunming, ChinaDepartment of Medical, Qinghai Provincial People’s Hospital, Xining, ChinaDepartment of General Surgery, Qinghai Provincial People’s Hospital, Xining, Qinghai, ChinaDepartment of Anesthesiology, Qinghai Provincial People’s Hospital, Xining, ChinaObjectiveTo study the application of thrombolysis diagram (TEG) and routine coagulation test in the evaluation of coagulation function in patients with hepatic hydatid.MethodsThe observation group consisted of 69 cases of hydatid liver patients undergoing elective combined segmenectomy, and the control group consisted of 69 healthy subjects. The correlation analysis of TEG, six coagulation items and PLT in the preoperative observation group and control group was conducted. The differences of TEG, hemagglutination six and PLT between the two groups were compared. TEG and coagulation function indexes of observation group were compared at different time during perioperative period.ResultsIn the control group, The time of blood cell aggregation (K) was negatively correlated with prothrombin time (PT), fibrinogen (FIB) and platelet count(PLT); The maximum strength of blood clot (MA) was positively correlated with PT, FIB and PLT; The rate of blood cell aggregation (Angle) is positively correlated with PT, FIB and PLT; the comprehensive index of blood coagulation (CI) was positively correlated with FIB and PLT. The reaction time of blood coagulation (R) of observation group was positively correlated with PT; MA was positively correlated with PT, FIB and PLT; MA was negatively correlated with thrombin time (TT). activated partial thromboplastin time (APTT), D-dimer (DD), PLT, R value, K value, Angle, MA and CI were compared between the two groups, and the differences were statistically significant (P<0.05). Compared with T1, APTT, R value, Angle and MA in observation group were significantly decreased at T2 and T3 (P<0.05); Compared with T1, PT, TT, FIB and K values had no significant changes (P>0.05).ConclusionThe coagulation function of liver hydatid patients was relatively low during the perioperative period, TEG is more sensitive to changes in perioperative coagulation function and can comprehensively understand the patient’s coagulation state.https://www.frontiersin.org/articles/10.3389/fonc.2025.1603148/fullcoagulation abnormalitieshepatic echinococcosishypohepatiaplatelet aggregation functionthromboelastography (TEG) |
| spellingShingle | Xing Zheng Li Yuan Bingxian Wang Genkui Li Jing Wang Jide A Zongzhao He Thromboelastography for the evaluation of coagulation function in patients with hepatic echinococcosis during the perioperative period: a retrospective study Frontiers in Oncology coagulation abnormalities hepatic echinococcosis hypohepatia platelet aggregation function thromboelastography (TEG) |
| title | Thromboelastography for the evaluation of coagulation function in patients with hepatic echinococcosis during the perioperative period: a retrospective study |
| title_full | Thromboelastography for the evaluation of coagulation function in patients with hepatic echinococcosis during the perioperative period: a retrospective study |
| title_fullStr | Thromboelastography for the evaluation of coagulation function in patients with hepatic echinococcosis during the perioperative period: a retrospective study |
| title_full_unstemmed | Thromboelastography for the evaluation of coagulation function in patients with hepatic echinococcosis during the perioperative period: a retrospective study |
| title_short | Thromboelastography for the evaluation of coagulation function in patients with hepatic echinococcosis during the perioperative period: a retrospective study |
| title_sort | thromboelastography for the evaluation of coagulation function in patients with hepatic echinococcosis during the perioperative period a retrospective study |
| topic | coagulation abnormalities hepatic echinococcosis hypohepatia platelet aggregation function thromboelastography (TEG) |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1603148/full |
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