A new biocompatible COF-MCM nanoporous hybrid DDS for pH-controlled delivery of curcumin

A new biocompatible COF-MCM nanoporous hybrid DDS for pH-controlled delivery of curcumin

Abstract A novel polyimide-bridge covalent organic framework-based (PI-COF) hybrid was synthesized through simple green chemistry between PI-COF and MCM-NH2 monomers as a pH-sensitive anticancer curcumin (C) delivery system. The synthesized nanohybrid was crystalline in nature with an improved surfa...

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Bibliographic Details
Main Authors: R. Foulady-Dehaghi, Sh. Sohrabnezhad, M. Hadavi
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Drug delivery
Covalent organic framework
Curcumin
pH-sensitive
Anticancer
Online Access:https://doi.org/10.1038/s41598-024-83614-x
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