GPRASP protein deficiency triggers lymphoproliferative disease by affecting B‐cell differentiation
Abstract Gprasp1 and Gprasp2 encode proteins that control the stability and cellular trafficking of CXCR4, a master regulator of hematopoiesis whose dynamic regulation is required for appropriate trafficking of B‐cells in the germinal center (GC). Here, we report that Gprasp1 and Gprasp2‐deficient B...
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| Main Authors: | Antonio Morales‐Hernández, Emilia Kooienga, Heather Sheppard, Gabriela Gheorghe, Claire Caprio, Ashley Chabot, Shannon McKinney‐Freeman |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-11-01
|
| Series: | HemaSphere |
| Online Access: | https://doi.org/10.1002/hem3.70037 |
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