GPRASP protein deficiency triggers lymphoproliferative disease by affecting B‐cell differentiation

Abstract Gprasp1 and Gprasp2 encode proteins that control the stability and cellular trafficking of CXCR4, a master regulator of hematopoiesis whose dynamic regulation is required for appropriate trafficking of B‐cells in the germinal center (GC). Here, we report that Gprasp1 and Gprasp2‐deficient B...

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Bibliographic Details
Main Authors: Antonio Morales‐Hernández, Emilia Kooienga, Heather Sheppard, Gabriela Gheorghe, Claire Caprio, Ashley Chabot, Shannon McKinney‐Freeman
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:HemaSphere
Online Access:https://doi.org/10.1002/hem3.70037
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