Correlation between variant allele frequency and mean tumor molecules with tumor burden in patients with solid tumors

Correlation between variant allele frequency and mean tumor molecules with tumor burden in patients with solid tumors

Several studies have demonstrated the prognostic value of circulating tumor DNA (ctDNA); however, the correlation of mean tumor molecules (MTM)/ml of plasma and mean variant allele frequency (mVAF; %) with clinical parameters is yet to be understood. In this study, we analyzed ctDNA data in a pan‐ca...

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Main Authors: Ekaterina Kalashnikova, Vasily N. Aushev, Allyson Koyen Malashevich, Antony Tin, Shifra Krinshpun, Raheleh Salari, Carly Bess Scalise, Rosalyn Ram, Meenakshi Malhotra, Harini Ravi, Himanshu Sethi, Stephanie Sanchez, Robert Tanner Hagelstrom, Maxim Brevnov, Matthew Rabinowitz, Solomon Moshkevich, Bernhard G. Zimmermann, Minetta C. Liu, Alexey Aleshin
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Molecular Oncology
Subjects:
biomarkers
circulating tumor DNA
mean tumor molecules
variant allele frequency
Online Access:https://doi.org/10.1002/1878-0261.13557
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