Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis – A Report of 2 Cases
Introduction: Lichen planus (LP) is a chronic inflammatory dermatosis that causes plaques and itchy papules on the skin, as well as erosion and ulcers in the mucous membranes. LP is characterized by a dense dermal T-cell infiltration. Perieccrine inflammation can be seen in a variety of dermatoses,...
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Karger Publishers
2024-10-01
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| Series: | Case Reports in Dermatology |
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| Online Access: | https://beta.karger.com/Article/FullText/541695 |
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| author | Fatemeh Mohaghegh Zohre Khodashenas Mina Saber Haniyeh Sohrabi |
| author_facet | Fatemeh Mohaghegh Zohre Khodashenas Mina Saber Haniyeh Sohrabi |
| author_sort | Fatemeh Mohaghegh |
| collection | DOAJ |
| description | Introduction: Lichen planus (LP) is a chronic inflammatory dermatosis that causes plaques and itchy papules on the skin, as well as erosion and ulcers in the mucous membranes. LP is characterized by a dense dermal T-cell infiltration. Perieccrine inflammation can be seen in a variety of dermatoses, but genuine lymphocyte permeation of the secretory coil or lymphocytic syringotropism is a rare sign that is typically seen in mycosis fungoides. Case Presentation: In this study, we present 2 uncommon instances of lymphocytic syringotropism in LP. Histopathological examination revealed dense T-cell infiltration and lymphocytic involvement of eccrine glands, confirming syringotropism. Conclusion: Lymphocytic syringotropism is an uncommon finding in LP. Its presence broadens the histopathological spectrum of LP and highlights the need to differentiate it from lymphoproliferative disorders like mycosis fungoides. |
| format | Article |
| id | doaj-art-8b0945146b2b4b5eb0c7423f2529c2e8 |
| institution | Kabale University |
| issn | 1662-6567 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Dermatology |
| spelling | doaj-art-8b0945146b2b4b5eb0c7423f2529c2e82024-11-14T07:28:50ZengKarger PublishersCase Reports in Dermatology1662-65672024-10-0116122623310.1159/000541695541695Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis – A Report of 2 CasesFatemeh Mohaghegh0Zohre Khodashenas1Mina Saber2Haniyeh Sohrabi3https://orcid.org/0000-0003-3130-750XDepartment of Dermatology, Skin Diseases, and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Dermatology, Faculty of Medicine, Shahed University, Tehran, IranDepartment of Dermatology, Skin Diseases, and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, IranIntroduction: Lichen planus (LP) is a chronic inflammatory dermatosis that causes plaques and itchy papules on the skin, as well as erosion and ulcers in the mucous membranes. LP is characterized by a dense dermal T-cell infiltration. Perieccrine inflammation can be seen in a variety of dermatoses, but genuine lymphocyte permeation of the secretory coil or lymphocytic syringotropism is a rare sign that is typically seen in mycosis fungoides. Case Presentation: In this study, we present 2 uncommon instances of lymphocytic syringotropism in LP. Histopathological examination revealed dense T-cell infiltration and lymphocytic involvement of eccrine glands, confirming syringotropism. Conclusion: Lymphocytic syringotropism is an uncommon finding in LP. Its presence broadens the histopathological spectrum of LP and highlights the need to differentiate it from lymphoproliferative disorders like mycosis fungoides.https://beta.karger.com/Article/FullText/541695lichen planusmycosis fungoidessyringotropic lichen planus |
| spellingShingle | Fatemeh Mohaghegh Zohre Khodashenas Mina Saber Haniyeh Sohrabi Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis – A Report of 2 Cases Case Reports in Dermatology lichen planus mycosis fungoides syringotropic lichen planus |
| title | Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis – A Report of 2 Cases |
| title_full | Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis – A Report of 2 Cases |
| title_fullStr | Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis – A Report of 2 Cases |
| title_full_unstemmed | Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis – A Report of 2 Cases |
| title_short | Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis – A Report of 2 Cases |
| title_sort | syringotropic lichen planus an unusual presentation of a common dermatosis a report of 2 cases |
| topic | lichen planus mycosis fungoides syringotropic lichen planus |
| url | https://beta.karger.com/Article/FullText/541695 |
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