PKMζ, a Brain-specific PKCζ Isoform, is Required for Glycolysis and Myofibroblastic Activation of Hepatic Stellate CellsSummary

Background & Aims: Transforming growth factor (TGF)β1 induces plasma membrane (PM) accumulation of glucose transporter 1 (Glut1) required for glycolysis of hepatic stellate cells (HSCs) and HSC activation. This study aimed to understand how Glut1 is anchored/docked onto the PM of HSCs. Metho...

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Bibliographic Details
Main Authors: Xianghu Wang, Yuanguo Wang, Bing Bai, Aurpita Shaha, Wenming Bao, Lianping He, Tian Wang, Gaspar J. Kitange, Ningling Kang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X2400184X
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