Monitoring Histone Deacetylase Inhibition In Vivo: Noninvasive Magnetic Resonance Spectroscopy Method

Monitoring Histone Deacetylase Inhibition In Vivo: Noninvasive Magnetic Resonance Spectroscopy Method

Histone deacetylase inhibitors (HDACis) are emerging as promising and selective antitumor agents. However, HDACis can lead to tumor stasis rather than shrinkage, in which case, traditional imaging methods are not adequate to monitor response. Consequently, novel approaches are needed. We have shown...

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Bibliographic Details
Main Authors: Madhuri Sankaranarayanapillai, William P. Tong, Qing Yuan, James A. Bankson, Hagit Dafni, William G. Bornmann, Suren Soghomonyan, Ashutosh Pal, Marc S. Ramirez, Douglas Webb, Kumaralal Kaluarachchi, Juri G. Gelovani, Sabrina M. Ronen
Format: Article
Language:English
Published: SAGE Publishing 2008-03-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2008.0011
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