Clinical value of mean platelet volume/lymphocyte ratio and degree of coronary artery disease in patients with chronic kidney disease
ObjectiveTo investigate the relationship between mean platelet volume to lymphocyte ratio （MPVLR） and the degree of coronary artery disease in patients with chronic kidney disease （CKD） and its clinical significance.MethodsThe clinical data of 111 patients with chronic kidney disease diagnosed by co...
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Editorial Department of Journal of Clinical Nephrology
2022-05-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.05.003 |
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| author | Li Ying-bin Li Sheng-kai |
| author_facet | Li Ying-bin Li Sheng-kai |
| author_sort | Li Ying-bin |
| collection | DOAJ |
| description | ObjectiveTo investigate the relationship between mean platelet volume to lymphocyte ratio （MPVLR） and the degree of coronary artery disease in patients with chronic kidney disease （CKD） and its clinical significance.MethodsThe clinical data of 111 patients with chronic kidney disease diagnosed by coronary angiography in our affiliated hospital in recent 6 years were analyzed retrospectively.The Gensini scoring was used to assess the severity of coronary artery disease.The data were divided into three groups： group A （mild，29 cases） had 0-30 points；Group B （moderate，23 cases） had 31-60 points，and group C （severe，59 cases） had >60 points.First，the related factors affecting coronary artery disease were analyzed by univariate analysis.On this basis，the risk factors and protective factors were determined by Logistic regression analysis.Finally，the predictive value was determined by ROC curve.ResultsUnivariate analysis showed that there was no significant difference in general data among the 3 groups （<italic>P</italic>>0.05），but there were significant differences in laboratory indicators such as albumin，uric acid，high density lipoprotein cholesterol （HDL-C） and MPVLR （<italic>P</italic><0.05）.High MPVLR level was an independent risk factor for high Gensini integration （<italic>OR</italic>=1.115，95%<italic>CI</italic> 1.009-1.239，<italic>P</italic>=0.047），and HDL-C was a protective factor.ConclusionsIn patients with chronic kidney disease，high MPVLR is an independent risk factor for the severity of coronary artery disease，and has the application value in predicting the severity of coronary artery disease. |
| format | Article |
| id | doaj-art-8a9eb17d0481470e836f84db4f684424 |
| institution | Kabale University |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2022-05-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-8a9eb17d0481470e836f84db4f6844242025-08-20T03:53:03ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902022-05-012236536926618004Clinical value of mean platelet volume/lymphocyte ratio and degree of coronary artery disease in patients with chronic kidney diseaseLi Ying-binLi Sheng-kaiObjectiveTo investigate the relationship between mean platelet volume to lymphocyte ratio （MPVLR） and the degree of coronary artery disease in patients with chronic kidney disease （CKD） and its clinical significance.MethodsThe clinical data of 111 patients with chronic kidney disease diagnosed by coronary angiography in our affiliated hospital in recent 6 years were analyzed retrospectively.The Gensini scoring was used to assess the severity of coronary artery disease.The data were divided into three groups： group A （mild，29 cases） had 0-30 points；Group B （moderate，23 cases） had 31-60 points，and group C （severe，59 cases） had >60 points.First，the related factors affecting coronary artery disease were analyzed by univariate analysis.On this basis，the risk factors and protective factors were determined by Logistic regression analysis.Finally，the predictive value was determined by ROC curve.ResultsUnivariate analysis showed that there was no significant difference in general data among the 3 groups （<italic>P</italic>>0.05），but there were significant differences in laboratory indicators such as albumin，uric acid，high density lipoprotein cholesterol （HDL-C） and MPVLR （<italic>P</italic><0.05）.High MPVLR level was an independent risk factor for high Gensini integration （<italic>OR</italic>=1.115，95%<italic>CI</italic> 1.009-1.239，<italic>P</italic>=0.047），and HDL-C was a protective factor.ConclusionsIn patients with chronic kidney disease，high MPVLR is an independent risk factor for the severity of coronary artery disease，and has the application value in predicting the severity of coronary artery disease.http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.05.003Chronic kidney diseaseCoronary diseaseGensini integralMean platelet volume/lymphocyte ratio |
| spellingShingle | Li Ying-bin Li Sheng-kai Clinical value of mean platelet volume/lymphocyte ratio and degree of coronary artery disease in patients with chronic kidney disease Linchuang shenzangbing zazhi Chronic kidney disease Coronary disease Gensini integral Mean platelet volume/lymphocyte ratio |
| title | Clinical value of mean platelet volume/lymphocyte ratio and degree of coronary artery disease in patients with chronic kidney disease |
| title_full | Clinical value of mean platelet volume/lymphocyte ratio and degree of coronary artery disease in patients with chronic kidney disease |
| title_fullStr | Clinical value of mean platelet volume/lymphocyte ratio and degree of coronary artery disease in patients with chronic kidney disease |
| title_full_unstemmed | Clinical value of mean platelet volume/lymphocyte ratio and degree of coronary artery disease in patients with chronic kidney disease |
| title_short | Clinical value of mean platelet volume/lymphocyte ratio and degree of coronary artery disease in patients with chronic kidney disease |
| title_sort | clinical value of mean platelet volume lymphocyte ratio and degree of coronary artery disease in patients with chronic kidney disease |
| topic | Chronic kidney disease Coronary disease Gensini integral Mean platelet volume/lymphocyte ratio |
| url | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.05.003 |
| work_keys_str_mv | AT liyingbin clinicalvalueofmeanplateletvolumelymphocyteratioanddegreeofcoronaryarterydiseaseinpatientswithchronickidneydisease AT lishengkai clinicalvalueofmeanplateletvolumelymphocyteratioanddegreeofcoronaryarterydiseaseinpatientswithchronickidneydisease |